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    Bile acids in regulation of intestinal physiology.

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    Authors
    Keating, Niamh
    Keely, Stephen J
    Affiliation
    Department of Molecular Medicine, Royal College of Surgeons in Ireland Education and Research Centre, Smurfit Building, Beaumont Hospital, Dublin 9, Ireland.
    Issue Date
    2009-10
    MeSH
    Animals
    Bile
    Bile Acids and Salts
    Dietary Fats
    Digestion
    Enterocytes
    Gastrointestinal Motility
    Humans
    Intestinal Absorption
    Intestinal Mucosa
    Intestine, Small
    Intestines
    Liver
    Receptors, Cytoplasmic and Nuclear
    Receptors, G-Protein-Coupled
    Signal Transduction
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    Citation
    Bile acids in regulation of intestinal physiology. 2009, 11 (5):375-82 Curr Gastroenterol Rep
    Journal
    Current gastroenterology reports
    URI
    http://hdl.handle.net/10147/127273
    PubMed ID
    19765365
    Abstract
    In addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.
    Item Type
    Article
    Language
    en
    ISSN
    1534-312X
    Collections
    Beaumont Hospital

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