Affiliation
Department of Molecular Medicine, Royal College of Surgeons in Ireland Education and Research Centre, Smurfit Building, Beaumont Hospital, Dublin 9, Ireland.Issue Date
2009-10MeSH
AnimalsBile
Bile Acids and Salts
Dietary Fats
Digestion
Enterocytes
Gastrointestinal Motility
Humans
Intestinal Absorption
Intestinal Mucosa
Intestine, Small
Intestines
Liver
Receptors, Cytoplasmic and Nuclear
Receptors, G-Protein-Coupled
Signal Transduction
Metadata
Show full item recordCitation
Bile acids in regulation of intestinal physiology. 2009, 11 (5):375-82 Curr Gastroenterol RepJournal
Current gastroenterology reportsPubMed ID
19765365Abstract
In addition to their roles in facilitating lipid digestion and absorption, bile acids are recognized as important regulators of intestinal function. Exposure to bile acids can dramatically influence intestinal transport and barrier properties; in recent years, they have also become appreciated as important factors in regulating cell growth and survival. Indeed, few cells reside within the intestinal mucosa that are not altered to some degree by exposure to bile acids. The past decade saw great advances in the knowledge of how bile acids exert their actions at the cellular and molecular levels. In this review, we summarize the current understanding of the role of bile acids in regulation of intestinal physiology.Item Type
ArticleLanguage
enISSN
1534-312XCollections
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