Show simple item record

dc.contributor.authorKeeling, Aoife N
dc.contributor.authorKhalidi, Karim
dc.contributor.authorLeong, Sum
dc.contributor.authorWang, Tim T
dc.contributor.authorAyyoub, Alaa S
dc.contributor.authorMcGrath, Frank P
dc.contributor.authorAthanasiou, Thanos
dc.contributor.authorLee, Michael J
dc.date.accessioned2011-04-05T15:32:57Z
dc.date.available2011-04-05T15:32:57Z
dc.date.issued2011-03
dc.identifier.citationBelow knee angioplasty in elderly patients: Predictors of major adverse clinical outcomes. 2011, 77 (3):483-9 Eur J Radiolen
dc.identifier.issn1872-7727
dc.identifier.pmid19765932
dc.identifier.doi10.1016/j.ejrad.2009.08.011
dc.identifier.urihttp://hdl.handle.net/10147/127272
dc.description.abstractTo determine predictors of clinical outcome following percutaneous transluminal angioplasty (PTA) in elderly patients with below knee atherosclerotic lesions causing intermittent claudication (IC) or critical limb ischaemia (CLI).
dc.description.abstractOver 7.5 years, 76 patients (CLI 72%, n=55) underwent below knee PTA. The composite end-point of interest was major adverse clinical outcome (MACO) of the treated limb at follow-up which was defined as clinical failure, need for subsequent endovascular or surgical revascularization or amputation. Actuarial freedom from MACO was assessed using Kaplan-Meier curves and multivariable Cox proportional hazards regression.
dc.description.abstractIC was improved in 95% at mean 3.4 years (range 0.5-108 months). Successful limb salvage and ulcer healing were seen in 73% with CLI. Most failures were in the CLI group (27% CLI vs. 5% IC), with an amputation rate of 16% for CLI vs. 5% for IC and persistent ulceration in 24% of CLI. Significant independent predictors of MACO were ulceration (hazard ratio 4.02, 95% CI=1.55-10.38) and family history of atherosclerosis (hazard ratio 2.53, 95% CI=1.1-5.92).
dc.description.abstractPrimary below knee PTA is a feasible therapeutic option in this elderly population. Limb ulceration and family history of atherosclerosis may be independent predictors of adverse outcome.
dc.language.isoenen
dc.titleBelow knee angioplasty in elderly patients: Predictors of major adverse clinical outcomes.en
dc.typeArticle In Pressen
dc.contributor.departmentDepartment of Academic Radiology, Beaumont Hospital, Beaumont Road, Dublin 9, Ireland.en
dc.identifier.journalEuropean journal of radiologyen
dc.description.provinceLeinster
html.description.abstractTo determine predictors of clinical outcome following percutaneous transluminal angioplasty (PTA) in elderly patients with below knee atherosclerotic lesions causing intermittent claudication (IC) or critical limb ischaemia (CLI).
html.description.abstractOver 7.5 years, 76 patients (CLI 72%, n=55) underwent below knee PTA. The composite end-point of interest was major adverse clinical outcome (MACO) of the treated limb at follow-up which was defined as clinical failure, need for subsequent endovascular or surgical revascularization or amputation. Actuarial freedom from MACO was assessed using Kaplan-Meier curves and multivariable Cox proportional hazards regression.
html.description.abstractIC was improved in 95% at mean 3.4 years (range 0.5-108 months). Successful limb salvage and ulcer healing were seen in 73% with CLI. Most failures were in the CLI group (27% CLI vs. 5% IC), with an amputation rate of 16% for CLI vs. 5% for IC and persistent ulceration in 24% of CLI. Significant independent predictors of MACO were ulceration (hazard ratio 4.02, 95% CI=1.55-10.38) and family history of atherosclerosis (hazard ratio 2.53, 95% CI=1.1-5.92).
html.description.abstractPrimary below knee PTA is a feasible therapeutic option in this elderly population. Limb ulceration and family history of atherosclerosis may be independent predictors of adverse outcome.


Files in this item

Thumbnail
Name:
Publisher version

This item appears in the following Collection(s)

Show simple item record