Authors
Murphy, G MAffiliation
Department of Dermatology, Beaumont & Mater Misericordiae Hospital, Dublin, Ireland. gmurphyoffice@eircom.netIssue Date
2009-11MeSH
AnimalsApoptosis
DNA Damage
Humans
Immunosuppression
Mice
Mice, Inbred C57BL
Neoplasms, Radiation-Induced
Skin
Ultraviolet Rays
Metadata
Show full item recordCitation
Ultraviolet radiation and immunosuppression. 2009, 161 Suppl 3:90-5 Br. J. Dermatol.Journal
The British journal of dermatologyDOI
10.1111/j.1365-2133.2009.09455.xPubMed ID
19775363Abstract
Ultraviolet (UV) radiation is a complete carcinogen. The effects of UV radiation are mediated via direct damage to cellular DNA in the skin and suppression of image surveillance mechanisms. In the context of organ transplantation, addiction of drugs which suppress the immune system add greatly to the carcinogenicity of UV radiation. This review considers the mechanisms of such effects.Item Type
ArticleLanguage
enISSN
1365-2133ae974a485f413a2113503eed53cd6c53
10.1111/j.1365-2133.2009.09455.x
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