Cannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence.
AffiliationDepartment of Psychiatry, Royal College of Surgeons in Ireland and Beaumont Hospital, Dublin, Ireland.
Age of Onset
Child Abuse, Sexual
Psychiatric Status Rating Scales
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CitationCannabis use and childhood trauma interact additively to increase the risk of psychotic symptoms in adolescence. 2010, 40 (10):1627-34 Psychol Med
AbstractOur finding of a greater than additive interaction between childhood trauma and cannabis use may have implications for the identification of individuals at high risk of experiencing psychotic symptoms. For example, measures to actively discourage or intensively treat cannabis use in children and adolescents who have experienced abuse may help to prevent the development of psychosis in this vulnerable group. Our findings require replication in larger samples to confirm this interaction effect.