• Iron status and chronic kidney disease predict restless legs syndrome in an older hospital population.

      Quinn, Colin; Uzbeck, Mateen; Saleem, Imran; Cotter, Paul; Ali, Javed; O'Malley, Grainne; Gilmartin, J J; O'Keeffe, Shaun T; Departments of Geriatric Medicine, Merlin Park University Hospital, Galway, Ireland. (2011-03)
      Iron deficiency is important in the pathogenesis of restless legs syndrome (RLS), and serum ferritin measurement, using a cutoff of 45-50ng/ml, is widely recommended as the optimal screening test for iron deficiency in RLS. Serum ferritin often increases with inflammation, and a higher cutoff may be better in those with acute and chronic inflammatory conditions, including those with chronic kidney disease (CKD).