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dc.contributor.authorPhelan, P J
dc.contributor.authorWalshe, J J
dc.contributor.authorAl-Aradi, A
dc.contributor.authorGarvey, J P
dc.contributor.authorFinnegan, K
dc.contributor.authorO'Kelly, P
dc.contributor.authorMcWilliams, J
dc.contributor.authorTi, J P
dc.contributor.authorMorrin, M M
dc.contributor.authorMorgan, N
dc.contributor.authorConlon, P J
dc.date.accessioned2011-03-31T12:52:01Z
dc.date.available2011-03-31T12:52:01Z
dc.date.issued2010-05
dc.identifier.citationEncapsulating peritoneal sclerosis: experience of a tertiary referral center. 2010, 32 (4):459-63 Ren Failen
dc.identifier.issn1525-6049
dc.identifier.pmid20446784
dc.identifier.doi10.3109/08860221003658274
dc.identifier.urihttp://hdl.handle.net/10147/126547
dc.description.abstractEncapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.
dc.description.abstractWe retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspected cases were confirmed at laparotomy. Multifactorial models adjusted for potentially confounding variables such as age and sex.
dc.description.abstractEleven cases of EPS were identified giving a prevalence rate of 1.98%. Median duration on PD was substantially longer in affected versus unaffected patients (42.5 months versus 13.8 months; p = 0.0002). EPS patients had experienced a mean of 3.54 previous cases of peritonitis (1 infection per year versus 0.71 per year in unaffected patients; p = 0.075). Six patients died (54.5%) due to intra-abdominal sepsis including all five who presented with small bowel obstruction. Three patients had an omentectomy and adhesiolysis performed with a successful outcome.
dc.description.abstractOur study reinforces the link between duration on PD and EPS. While mortality was high in our cohort, emerging surgical techniques demonstrate a favorable outcome that can be achieved even in severely affected cases.
dc.language.isoenen
dc.subject.meshAdult
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIreland
dc.subject.meshKidney Failure, Chronic
dc.subject.meshLogistic Models
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshPeritoneal Dialysis, Continuous Ambulatory
dc.subject.meshPeritoneal Fibrosis
dc.subject.meshPrevalence
dc.subject.meshRetrospective Studies
dc.subject.meshRisk Factors
dc.subject.meshStatistics, Nonparametric
dc.titleEncapsulating peritoneal sclerosis: experience of a tertiary referral center.en
dc.typeArticleen
dc.contributor.departmentDepartment of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.comen
dc.identifier.journalRenal failureen
dc.description.provinceLeinster
html.description.abstractEncapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.
html.description.abstractWe retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspected cases were confirmed at laparotomy. Multifactorial models adjusted for potentially confounding variables such as age and sex.
html.description.abstractEleven cases of EPS were identified giving a prevalence rate of 1.98%. Median duration on PD was substantially longer in affected versus unaffected patients (42.5 months versus 13.8 months; p = 0.0002). EPS patients had experienced a mean of 3.54 previous cases of peritonitis (1 infection per year versus 0.71 per year in unaffected patients; p = 0.075). Six patients died (54.5%) due to intra-abdominal sepsis including all five who presented with small bowel obstruction. Three patients had an omentectomy and adhesiolysis performed with a successful outcome.
html.description.abstractOur study reinforces the link between duration on PD and EPS. While mortality was high in our cohort, emerging surgical techniques demonstrate a favorable outcome that can be achieved even in severely affected cases.


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