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    Encapsulating peritoneal sclerosis: experience of a tertiary referral center.

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    Authors
    Phelan, P J
    Walshe, J J
    Al-Aradi, A
    Garvey, J P
    Finnegan, K
    O'Kelly, P
    McWilliams, J
    Ti, J P
    Morrin, M M
    Morgan, N
    Conlon, P J
    Show allShow less
    Affiliation
    Department of Nephrology, Beaumont Hospital, Dublin 9, Ireland. paulphel@gmail.com
    Issue Date
    2010-05
    MeSH
    Adult
    Female
    Humans
    Ireland
    Kidney Failure, Chronic
    Logistic Models
    Male
    Middle Aged
    Peritoneal Dialysis, Continuous Ambulatory
    Peritoneal Fibrosis
    Prevalence
    Retrospective Studies
    Risk Factors
    Statistics, Nonparametric
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    Citation
    Encapsulating peritoneal sclerosis: experience of a tertiary referral center. 2010, 32 (4):459-63 Ren Fail
    Journal
    Renal failure
    URI
    http://hdl.handle.net/10147/126547
    DOI
    10.3109/08860221003658274
    PubMed ID
    20446784
    Abstract
    Encapsulating peritoneal sclerosis (EPS) is arguably the most serious complication of chronic peritoneal dialysis (PD) therapy with extremely high mortality rates. We aimed to establish the rates of EPS and factors associated with its development in a single center.
    We retrospectively reviewed the records of all our PD patients from 1 January 1989 until 31 December 2008. All suspected cases were confirmed at laparotomy. Multifactorial models adjusted for potentially confounding variables such as age and sex.
    Eleven cases of EPS were identified giving a prevalence rate of 1.98%. Median duration on PD was substantially longer in affected versus unaffected patients (42.5 months versus 13.8 months; p = 0.0002). EPS patients had experienced a mean of 3.54 previous cases of peritonitis (1 infection per year versus 0.71 per year in unaffected patients; p = 0.075). Six patients died (54.5%) due to intra-abdominal sepsis including all five who presented with small bowel obstruction. Three patients had an omentectomy and adhesiolysis performed with a successful outcome.
    Our study reinforces the link between duration on PD and EPS. While mortality was high in our cohort, emerging surgical techniques demonstrate a favorable outcome that can be achieved even in severely affected cases.
    Item Type
    Article
    Language
    en
    ISSN
    1525-6049
    ae974a485f413a2113503eed53cd6c53
    10.3109/08860221003658274
    Scopus Count
    Collections
    Beaumont Hospital

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