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    Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.

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    Authors
    Power, Sarah
    Slattery, Michael M
    Lee, Michael J
    Affiliation
    Department of Radiology, Beaumont Hospital, Beaumont Road, PO Box 1297, Dublin 9, Ireland.
    Issue Date
    2010-09-16
    
    Metadata
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    Citation
    Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention. 2010: Cardiovasc Intervent Radiol
    Journal
    Cardiovascular and interventional radiology
    URI
    http://hdl.handle.net/10147/126170
    DOI
    10.1007/s00270-010-9967-y
    PubMed ID
    20845040
    Abstract
    Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.
    Item Type
    Article In Press
    ISSN
    1432-086X
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00270-010-9967-y
    Scopus Count
    Collections
    Beaumont Hospital

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