Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention.
Affiliation
Department of Radiology, Beaumont Hospital, Beaumont Road, PO Box 1297, Dublin 9, Ireland.Issue Date
2010-09-16
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Nanotechnology and its Relationship to Interventional Radiology. Part II: Drug Delivery, Thermotherapy, and Vascular Intervention. 2010: Cardiovasc Intervent RadiolJournal
Cardiovascular and interventional radiologyDOI
10.1007/s00270-010-9967-yPubMed ID
20845040Abstract
Nanotechnology can be defined as the design, creation, and manipulation of structures on the nanometer scale. This two-part review is intended to acquaint the interventionalist with the field of nanotechnology, and provide an overview of potential applications, while highlighting advances relevant to interventional radiology. Part 2 of the article concentrates on drug delivery, thermotherapy, and vascular intervention. In oncology, advances in drug delivery allow for improved efficacy, decreased toxicity, and greater potential for targeted therapy. Magnetic nanoparticles show potential for use in thermotherapy treatments of various tumours, and the effectiveness of radiofrequency ablation can be enhanced with nanoparticle chemotherapy agents. In vascular intervention, much work is focused on prevention of restenosis through developments in stent technology and systems for localised drug delivery to vessel walls. Further areas of interest include applications for thrombolysis and haemostasis.Item Type
Article In PressISSN
1432-086Xae974a485f413a2113503eed53cd6c53
10.1007/s00270-010-9967-y
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