Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours.
Affiliation
Department of Molecular Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland.Issue Date
2011-01-18MeSH
Antineoplastic Agents, HormonalBreast Neoplasms
Cohort Studies
Cytosol
Female
Humans
Oligonucleotide Array Sequence Analysis
Phospholipases A2
Prognosis
RNA, Messenger
Receptor, Epidermal Growth Factor
Reverse Transcriptase Polymerase Chain Reaction
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Cytosolic phospholipase A2-α expression in breast cancer is associated with EGFR expression and correlates with an adverse prognosis in luminal tumours. 2011, 104 (2):338-44 Br. J. CancerJournal
British journal of cancerDOI
10.1038/sj.bjc.6606025PubMed ID
21119660Additional Links
http://www.nature.com/bjc/journal/v104/n2/pdf/6606025a.pdfAbstract
This study shows a role of cPLA(2)α in luminal breast cancer progression, in which the enzyme could represent a novel therapeutic target and a predictive marker.Item Type
ArticleLanguage
enISSN
1532-1827ae974a485f413a2113503eed53cd6c53
10.1038/sj.bjc.6606025
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