The risk of arrhythmias following coronary artery bypass surgery: do smokers have a paradox effect?
AffiliationDepartment of Cardiothoracic Surgery, St. James's Hospital, Dublin 8, Ireland. email@example.com
Aged, 80 and over
Coronary Artery Bypass
Databases as Topic
MetadataShow full item record
CitationThe risk of arrhythmias following coronary artery bypass surgery: do smokers have a paradox effect? 2010, 11 (5):550-5 Interact Cardiovasc Thorac Surg
JournalInteractive cardiovascular and thoracic surgery
AbstractSmoking is reported to increase the risk of arrhythmias. However, there are limited data on its effects on arrhythmias following coronary artery bypass graft (CABG). This is a retrospective review of a prospective database of all CABG patients over an eight-year period. Our cohort (n=2813) was subdivided into: current (n=1169), former (n=837), and non-smokers (n=807). Predictors of arrhythmias following CABG in relation to smoking status were analysed. Atrial arrhythmias occurred in 942 patients (33%). Ventricular arrhythmias occurred in 48 patients (2%) and high-grade atrioventricular block occurred in five patients (0.2%). Arrhythmias were lower in current smokers than former and non-smokers (29% vs. 40% vs. 39%, respectively P<0.001). Logistic regression analysis showed 30% arrhythmia risk reduction in smokers compared to non-smokers [odds ratio (OR) 0.7, 95% confidence intervals (CI) 0.5-0.8] and this effect persisted after accounting for potential confounders while former smokers had the same risk as non-smokers (OR 1.04, CI 0.9-1.3). There were no significant differences in mortality. Smokers are less prone to develop arrhythmias following CABG. This paradox effect is lost in former smokers. This effect is possibly due to a lower state of hyper adrenergic stimulation observed in smokers than non-smokers following the stress of surgery.
- Effect of smoking on short-term outcome of patients undergoing coronary artery bypass surgery.
- Authors: Al-Sarraf N, Thalib L, Hughes A, Tolan M, Young V, McGovern E
- Issue date: 2008 Aug
- Meta-analysis of randomized trials on the efficacy of posterior pericardiotomy in preventing atrial fibrillation after coronary artery bypass surgery.
- Authors: Biancari F, Mahar MA
- Issue date: 2010 May
- Clinical depression, posttraumatic stress disorder, and comorbid depression and posttraumatic stress disorder as risk factors for in-hospital mortality after coronary artery bypass grafting surgery.
- Authors: Dao TK, Chu D, Springer J, Gopaldas RR, Menefee DS, Anderson T, Hiatt E, Nguyen Q
- Issue date: 2010 Sep
- [Impact of smoking on the results of coronary artery bypass surgery].
- Authors: Mortasawi A, Ashraf MN, Grayson AD, Oo AY
- Issue date: 2004 May
- Effect of smoking status on mortality and morbidity following coronary artery bypass surgery.
- Authors: Ashraf MN, Mortasawi A, Grayson AD, Oo AY
- Issue date: 2004 Oct