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dc.contributor.authorO'Reilly, R
dc.contributor.authorRyan, S
dc.contributor.authorDonoghue, V
dc.contributor.authorSaidlear, C
dc.contributor.authorTwomey, E
dc.contributor.authorSlattery, D M
dc.date.accessioned2011-03-16T15:52:12Z
dc.date.available2011-03-16T15:52:12Z
dc.date.issued2010-02
dc.identifier.citationCumulative radiation exposure in children with cystic fibrosis. 2010, 103 (2):43-6 Ir Med Jen
dc.identifier.issn0332-3102
dc.identifier.pmid20666054
dc.identifier.urihttp://hdl.handle.net/10147/124875
dc.description.abstractThis retrospective study calculated the cumulative radiation dose for children with cystic fibrosis (CF) attending a tertiary CF centre. Information on 77 children with a mean age of 9.5 years, a follow up time of 658 person years and 1757 studies including 1485 chest radiographs, 215 abdominal radiographs and 57 computed tomography (CT) scans, of which 51 were thoracic CT scans, were analysed. The average cumulative radiation dose was 6.2 (0.04-25) mSv per CF patient. Cumulative radiation dose increased with increasing age and number of CT scans and was greater in children who presented with meconium ileus. No correlation was identified between cumulative radiation dose and either lung function or patient microbiology cultures. Radiation carries a risk of malignancy and children are particularly susceptible. Every effort must be made to avoid unnecessary radiation exposure in these patients whose life expectancy is increasing.
dc.language.isoenen
dc.subject.meshAdolescent
dc.subject.meshChild
dc.subject.meshCystic Fibrosis
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshIleus
dc.subject.meshMale
dc.subject.meshRadiation Dosage
dc.subject.meshRadiography, Thoracic
dc.subject.meshRetrospective Studies
dc.subject.meshTomography, X-Ray Computed
dc.subject.meshYoung Adult
dc.titleCumulative radiation exposure in children with cystic fibrosis.en
dc.typeArticleen
dc.contributor.departmentChildren's University Hospital, Temple St, Dublin 1. roreilly@imperial.ac.uken
dc.identifier.journalIrish medical journalen
refterms.dateFOA2018-08-22T11:29:10Z
html.description.abstractThis retrospective study calculated the cumulative radiation dose for children with cystic fibrosis (CF) attending a tertiary CF centre. Information on 77 children with a mean age of 9.5 years, a follow up time of 658 person years and 1757 studies including 1485 chest radiographs, 215 abdominal radiographs and 57 computed tomography (CT) scans, of which 51 were thoracic CT scans, were analysed. The average cumulative radiation dose was 6.2 (0.04-25) mSv per CF patient. Cumulative radiation dose increased with increasing age and number of CT scans and was greater in children who presented with meconium ileus. No correlation was identified between cumulative radiation dose and either lung function or patient microbiology cultures. Radiation carries a risk of malignancy and children are particularly susceptible. Every effort must be made to avoid unnecessary radiation exposure in these patients whose life expectancy is increasing.


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