• Assisted reproductive technology treatment outcomes.

      Naasan, M; Waterstone, J; Johnston, M M; Nolan, A; Egan, D; Shamoun, O; Thompson, W; Roopnarinesingh, R; Wingfield, M; Harrison, R F; et al. (Irish Medical Journal (IMJ), 2012-05)
      Information on the outcomes of ART treatments in Ireland is not readily available to Irish practitioners. The data for hospital affiliated clinics has been made available for many years and is included in the hospital reports. We present a 10-year analysis of the Irish ART results voluntarily reported by six out of seven IVF clinics. The data was collected from published ESHRE reports and from results (2007-8) not yet published. Data collected included: number of clinics and ART cycles, female age, clinical and multiple pregnancy rates and treatment complications. The clinical pregnancy rate per embryo transfer was 31.7% for IVF and 29.8% for ICSI. The proportion of singleton, twin and triplet deliveries for IVF and ICSI combined was 75%, 23.35% and 1.64%. The rate of ovarian hyperstimulation was 0.8%. ART practice in Ireland is safe, effective and responsible. Financial and societal savings could result from the introduction of state funded IVF with compulsory eSET where recommended.
    • Does the Endometrial Scratch improve implantation rates?

      Chawla, S; Purandare, N; Mocanu, E; Hughe, C; Deignan, K; Naasan, M; Kirkham, C (Irish Medical Journal, 2015-07)
      Implantation is one of the most crucial steps in the process of reproduction. Implantation failure is often due to impaired uterine receptivity. Assisted Reproduction techniques are used in order to overcome fertility problems. The endometrial scratch (ES) is a relatively new technique that is said to improve the probability of a successful pregnancy in some women. 1 Although the exact mechanism of this process is still unknown 2 , the use of a catheter to cause local injury to the endometrial lining is suggested to initiate a healing process, thereby attracting immune markers and potentially improving implantation rates. The aim of this study is to assess whether the ES offered randomly to patients attending for ART results in a higher implantation rate in patients that avail of it compared to patients that do not have an endometrial scratch (non-ES).