AffiliationSleep Research Laboratory, St. Vincent's University Hospital, Dublin, Ireland. firstname.lastname@example.org
Continuous Positive Airway Pressure
Quality of Life
Sleep Apnea, Obstructive
MetadataShow full item record
CitationContinuous positive airway pressure therapy: new generations. 2010, 131:259-66 Indian J. Med. Res.
JournalThe Indian journal of medical research
AbstractContinuous positive airway pressure (CPAP) is the treatment of choice for obstructive sleep apnoea syndrome (OSAS). However, CPAP is not tolerated by all patients with OSAS and alternative modes of pressure delivery have been developed to overcome pressure intolerance, thereby improving patient comfort and adherence. Auto-adjustable positive airway pressure (APAP) devices may be utilised for the long-term management of OSAS and may also assist in the initial diagnosis of OSAS and titration of conventional CPAP therapy. Newer modalities such as C-Flex and A-Flex also show promise as treatment options in the future. However, the evidence supporting the use of these alternative modalities remains scant, in particular with regard to long-term cardiovascular outcomes. In addition, not all APAP devices use the same technological algorithms and data supporting individual APAP devices cannot be extrapolated to support all. Further studies are required to validate the roles of APAP, C-Flex and A-Flex. In the interim, standard CPAP therapy should continue as the mainstay of OSAS management.
- Comparison of three auto-adjusting positive pressure devices in patients with sleep apnoea.
- Authors: Nolan GM, Ryan S, O'connor TM, McNicholas WT
- Issue date: 2006 Jul
- The use of auto-titrating continuous positive airway pressure for treatment of adult obstructive sleep apnea. An American Academy of Sleep Medicine review.
- Authors: Berry RB, Parish JM, Hartse KM
- Issue date: 2002 Mar 15
- The value of auto-adjustable CPAP devices in pressure titration and treatment of patients with obstructive sleep apnea syndrome.
- Authors: Hertegonne K, Bauters F
- Issue date: 2010 Apr
- Efficacy and patient satisfaction with autoadjusting CPAP with variable expiratory pressure vs standard CPAP: a two-night randomized crossover trial.
- Authors: Mulgrew AT, Cheema R, Fleetham J, Ryan CF, Ayas NT
- Issue date: 2007 Mar
- Positive airway pressure initiation: a randomized controlled trial to assess the impact of therapy mode and titration process on efficacy, adherence, and outcomes.
- Authors: Kushida CA, Berry RB, Blau A, Crabtree T, Fietze I, Kryger MH, Kuna ST, Pegram GV Jr, Penzel T
- Issue date: 2011 Aug 1