Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008.
Authors
Kuijper, E JBarbut, F
Brazier, J S
Kleinkauf, N
Eckmanns, T
Lambert, M L
Drudy, D
Fitzpatrick, F
Wiuff, C
Brown, D J
Coia, J E
Pituch, H
Reichert, P
Even, J
Mossong, J
Widmer, A F
Olsen, K E
Allerberger, F
Notermans, D W
Delmée, M
Coignard, B
Wilcox, M
Patel, B
Frei, R
Nagy, E
Bouza, E
Marin, M
Akerlund, T
Virolainen-Julkunen, A
Lyytikäinen, O
Kotila, S
Ingebretsen, A
Smyth, B
Rooney, P
Poxton, I R
Monnet, D L
Affiliation
National Reference Laboratory for Clostridium difficile. Leiden University Medical Center, Leiden, The Netherlands.Issue Date
2008-07-31Keywords
COMMUNICABLE DISEASELocal subject classification
CLOSTRIDIUM DIFFICILEMeSH
Clostridium difficileDisease Outbreaks
Enterocolitis, Pseudomembranous
Europe
European Union
Humans
Polymerase Chain Reaction
Population Surveillance
Ribotyping
Metadata
Show full item recordCitation
Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. 2008, 13 (31): Euro Surveill.Journal
Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletinPubMed ID
18761903Additional Links
http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18942Abstract
Outbreaks of Clostridium difficile infections (CDI) with increased severity, high relapse rate and significant mortality have been related to the emergence of a new, hypervirulent C. difficile strain in North America and Europe. This emerging strain is referred to as PCR ribotype 027 (Type 027). Since 2005, individual countries have developed surveillance studies about the spread of type 027.C. difficile Type 027 has been reported in 16 European countries. It has been responsible for outbreaks in Belgium, Germany, Finland, France, Ireland, Luxembourg, The Netherlands, Switzerland and the United Kingdom (England, Wales, Northern Ireland and Scotland). It has also been detected in Austria, Denmark, Sweden, Norway, Hungary, Poland and Spain. Three countries experienced imported patients with CDI due to Type 027 who acquired the infection abroad.The antimicrobial resistance pattern is changing, and outbreaks due to clindamycin-resistant ermB positive Type 027 strains have occurred in three European countries. Ongoing epidemiological surveillance of cases of CDI, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of new, highly virulent clones.Item Type
ArticleLanguage
enISSN
1560-7917Collections
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