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    Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008.

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    C Diff article 2008
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    Authors
    Kuijper, E J
    Barbut, F
    Brazier, J S
    Kleinkauf, N
    Eckmanns, T
    Lambert, M L
    Drudy, D
    Fitzpatrick, F
    Wiuff, C
    Brown, D J
    Coia, J E
    Pituch, H
    Reichert, P
    Even, J
    Mossong, J
    Widmer, A F
    Olsen, K E
    Allerberger, F
    Notermans, D W
    Delmée, M
    Coignard, B
    Wilcox, M
    Patel, B
    Frei, R
    Nagy, E
    Bouza, E
    Marin, M
    Akerlund, T
    Virolainen-Julkunen, A
    Lyytikäinen, O
    Kotila, S
    Ingebretsen, A
    Smyth, B
    Rooney, P
    Poxton, I R
    Monnet, D L
    Show allShow less
    Affiliation
    National Reference Laboratory for Clostridium difficile. Leiden University Medical Center, Leiden, The Netherlands.
    Issue Date
    2008-07-31
    Keywords
    COMMUNICABLE DISEASE
    Local subject classification
    CLOSTRIDIUM DIFFICILE
    MeSH
    Clostridium difficile
    Disease Outbreaks
    Enterocolitis, Pseudomembranous
    Europe
    European Union
    Humans
    Polymerase Chain Reaction
    Population Surveillance
    Ribotyping
    
    Metadata
    Show full item record
    Citation
    Update of Clostridium difficile infection due to PCR ribotype 027 in Europe, 2008. 2008, 13 (31): Euro Surveill.
    Journal
    Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin
    URI
    http://hdl.handle.net/10147/104974
    PubMed ID
    18761903
    Additional Links
    http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18942
    Abstract
    Outbreaks of Clostridium difficile infections (CDI) with increased severity, high relapse rate and significant mortality have been related to the emergence of a new, hypervirulent C. difficile strain in North America and Europe. This emerging strain is referred to as PCR ribotype 027 (Type 027). Since 2005, individual countries have developed surveillance studies about the spread of type 027.C. difficile Type 027 has been reported in 16 European countries. It has been responsible for outbreaks in Belgium, Germany, Finland, France, Ireland, Luxembourg, The Netherlands, Switzerland and the United Kingdom (England, Wales, Northern Ireland and Scotland). It has also been detected in Austria, Denmark, Sweden, Norway, Hungary, Poland and Spain. Three countries experienced imported patients with CDI due to Type 027 who acquired the infection abroad.The antimicrobial resistance pattern is changing, and outbreaks due to clindamycin-resistant ermB positive Type 027 strains have occurred in three European countries. Ongoing epidemiological surveillance of cases of CDI, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of new, highly virulent clones.
    Item Type
    Article
    Language
    en
    ISSN
    1560-7917
    Collections
    Health Protection Surveillance Centre (HPSC)

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