National Maternity Hospital Holles St.http://hdl.handle.net/10147/1281652024-03-26T15:22:15Z2024-03-26T15:22:15ZMeasles Outbreaks Continue to Cause Concern.Murphy, J F Ahttp://hdl.handle.net/10147/6408382024-02-21T02:04:17Z2019-06-17T00:00:00ZMeasles Outbreaks Continue to Cause Concern.
Murphy, J F A
At the Europaediatrics in Dublin, 13-15 June 2019 there was a symposium on Mandatory vaccination.
Many pros and cons were voiced.
The deeper and more worrying issue is why such a debate is now considered necessary. It is difficult to
grasp why a proportion of a knowledgeable and well-educated group of parents would choose not to
vaccinate their children. Scientific progress in vaccination has been hard won. Governments provide it
free of costs to parents. It is the greatest or one of the greatest advances in children’s healthcare over
the last century. In Ireland in 1950, in the pre-Measles vaccination era there were 15,000 cases in a
single year. It is distressing to see these advances in disease prevention being undermined and
underused.
2019-06-17T00:00:00ZPredicting Spontaneous Preterm Birth.Kennedy, CO’Dwyer, Vhttp://hdl.handle.net/10147/6407652024-02-14T02:15:08Z2019-08-01T00:00:00ZPredicting Spontaneous Preterm Birth.
Kennedy, C; O’Dwyer, V
Preterm birth is defined as delivery prior to 37 completed weeks gestation. It is a leading cause of perinatal morbidity and mortality globally 1 with the incidence in Ireland approximately 7%. While advancements in perinatal care have improved survival rates for babies born early, significant complications can arise from pre-term birth including the possibility of neurodevelopmental delay, gastrointestinal and respiratory problems. Pre-term delivery can also have significant psychological and financial implications for families affected.2
Seventy percent of pre-term births occur spontaneously3 while in some cases early delivery may be medically indicated in the fetal or maternal interest.
2019-08-01T00:00:00ZThe Modified Sarnat Score in the Assessment of Neonatal Encephalopathy: A Quality Improvement Initiative.Power, B DMcGinley, JSweetman, DMurphy, J F Ahttp://hdl.handle.net/10147/6406562024-02-14T02:10:26Z2019-08-01T00:00:00ZThe Modified Sarnat Score in the Assessment of Neonatal Encephalopathy: A Quality Improvement Initiative.
Power, B D; McGinley, J; Sweetman, D; Murphy, J F A
The Sarnat score is an essential component in the assessment and evaluation of the infant with neonatal encephalopathy. This clinical tool provides physicians with a standardised approach to systematic neurological examination and documentation of pertinent neurological findings. The value of the Sarnat Score has increased with the advent of therapeutic hypothermia and the need to evaluate the neurological response to treatment.
2019-08-01T00:00:00ZTherapeutic Listening for Preterm Children with Sensory Dysregulation, Attention and Cognitive Problems.Slevin, MO'Connor, KSegurado, RMurphy, J F Ahttp://hdl.handle.net/10147/6406552024-02-14T02:10:33Z2020-01-16T00:00:00ZTherapeutic Listening for Preterm Children with Sensory Dysregulation, Attention and Cognitive Problems.
Slevin, M; O'Connor, K; Segurado, R; Murphy, J F A
Introduction Is Therapeutic Listening effective for children born preterm presenting with sensory dysregulation, attention and cognitive problems? Methods 22 children (BW<1500g) 3-4 years were enrolled in a single centre, prospective, assessor-blinded RTC. Outcome measures: Winnie-Dunn Sensory Profile; Peabody Developmental Motor Scales; Reynell Attention Scale; Preschool Language Scales – 3; RAPT; WPPSI – IV; Parent Review Questionnaires. Results The intervention group (n=9) showed better improvement in sensory processing, compared to controls (n=9) (6.4 fold improvement in sensation seeking; 5.0 in auditory processing; 4.0 in tactile processing). Six intervention children (67%) improved in vestibular processing. Attention levels improved for 9 (100%) children in the intervention group and for 7 (78%) in the control group. Higher level domains (Peabody motor skills, Auditory Comprehension, Expressive Communication, RAPT scale, and WPPSI scores) showed mixed results. Parents reported positive changes in their child’s development. Conclusion Therapeutic Listening (TL) is a feasible intervention for preterm children to improve attention levels and sensory processing skills.
2020-01-16T00:00:00ZHypotension in Preterm Infants (HIP) randomised trial.Dempsey, Eugene MBarrington, Keith JMarlow, NeilO'Donnell, Colm Patrick FinbarrMiletin, JanNaulaers, GunnarCheung, Po-YinCorcoran, John DavidEl-Khuffash, Afif FaisalBoylan, Geraldine BLivingstone, VickiPons, GerardMacko, JozefVan Laere, DavidWiedermannova, HanaStraňák, Zbyněkhttp://hdl.handle.net/10147/6312952022-02-04T01:49:52Z2021-02-24T00:00:00ZHypotension in Preterm Infants (HIP) randomised trial.
Dempsey, Eugene M; Barrington, Keith J; Marlow, Neil; O'Donnell, Colm Patrick Finbarr; Miletin, Jan; Naulaers, Gunnar; Cheung, Po-Yin; Corcoran, John David; El-Khuffash, Afif Faisal; Boylan, Geraldine B; Livingstone, Vicki; Pons, Gerard; Macko, Jozef; Van Laere, David; Wiedermannova, Hana; Straňák, Zbyněk
Objective: To determine whether restricting the use of inotrope after diagnosis of low blood pressure (BP) in the first 72 hours of life affects survival without significant brain injury at 36 weeks of postmenstrual age (PMA) in infants born before 28 weeks of gestation.
Design: Double-blind, placebo-controlled randomised trial. Caregivers were masked to group assignment.
Setting: 10 sites across Europe and Canada.
Participants: Infants born before 28 weeks of gestation were eligible if they had an invasive mean BP less than their gestational age that persisted for ≥15 min in the first 72 hours of life and a cerebral ultrasound free of significant (≥ grade 3) intraventricular haemorrhage.
Intervention: Participants were randomly assigned to saline bolus followed by either a dopamine infusion (standard management) or placebo (5% dextrose) infusion (restrictive management).
Primary outcome: Survival to 36 weeks of PMA without severe brain injury.
Results: The trial terminated early due to significant enrolment issues (7.7% of planned recruitment). 58 infants were enrolled between February 2015 and September 2017. The two groups were well matched for baseline variables. In the standard group, 18/29 (62%) achieved the primary outcome compared with 20/29 (69%) in the restrictive group (p=0.58). Additional treatments for low BP were used less frequently in the standard arm (11/29 (38%) vs 19/29 (66%), p=0.038).
Conclusion: Though this study lacked power, we did not detect major differences in clinical outcomes between standard or restrictive approach to treatment. These results will inform future studies in this area.
2021-02-24T00:00:00ZLatch On: A protocol for a multi-centre, randomised controlled trial of perinatal support to improve breastfeeding outcomes in women with a raised BMI.O'Reilly, Sharleen LO'Brien, Eileen CMcGuinness, DeniseMehegan, JohnCoughlan, BarbaraO'Brien, DeniseSzafranska, MarcelinaCallanan, SophieHughes, ShendaConway, Marie CBrosnan, MarySheehy, LucilleMurtagh, RosieO'Hagan, LorraineMurray, StephanieScallon, CharmaineDunn, ElizabethPower, PaulaWoodcock, MarieCarroll, AmyCorbett, MarieWalsh, MichelleKeogh, ReginaMcAuliffe, Fionnuala Mhttp://hdl.handle.net/10147/6312072022-01-29T03:15:55Z2021-04-08T00:00:00ZLatch On: A protocol for a multi-centre, randomised controlled trial of perinatal support to improve breastfeeding outcomes in women with a raised BMI.
O'Reilly, Sharleen L; O'Brien, Eileen C; McGuinness, Denise; Mehegan, John; Coughlan, Barbara; O'Brien, Denise; Szafranska, Marcelina; Callanan, Sophie; Hughes, Shenda; Conway, Marie C; Brosnan, Mary; Sheehy, Lucille; Murtagh, Rosie; O'Hagan, Lorraine; Murray, Stephanie; Scallon, Charmaine; Dunn, Elizabeth; Power, Paula; Woodcock, Marie; Carroll, Amy; Corbett, Marie; Walsh, Michelle; Keogh, Regina; McAuliffe, Fionnuala M
This protocol is for a multi-centre, randomised controlled trial of perinatal breastfeeding support among primiparous women with a BMI >25 kg/m2, using a previously-tested, multi-component intervention. The primary outcome is any breastfeeding at 3 months. The intervention will support mothers and their partners and spans from late pregnancy to six weeks postpartum. Intervention components include group antenatal breastfeeding education, individual face-to-face education in the immediate postnatal period, professional support to six weeks' postpartum and weekly phone calls in the immediate postpartum period from an International Board Certified Lactation Consultant (IBCLC). The intervention will target attitudes towards breastfeeding, breastfeeding self-efficacy, and subjective norms around infant feeding with the aim to normalise the behaviour.
2021-04-08T00:00:00ZPerinatal social work during the Covid-19 pandemic: Reflecting on concepts of time and liminality.Wilson, ElaineJackson, KayleneShannon, Aoifehttp://hdl.handle.net/10147/6311862022-01-28T02:11:59Z2021-03-01T00:00:00ZPerinatal social work during the Covid-19 pandemic: Reflecting on concepts of time and liminality.
Wilson, Elaine; Jackson, Kaylene; Shannon, Aoife
This article reflects upon the experiences of two perinatal, hospital social workers during the unprecedented time of the Covid-19 in Ireland, as discussed with their academic colleague. This encounter revealed the complexity of service delivery that emerged, when managing the needs of vulnerable clients whilst being mindful of personal safety. One of the social workers was pregnant so was conscious of possible risks to her unborn child, as well as her young family at home. The second social worker, her line manager, discusses the dilemmas associated with the management of risk when allocating staff to contexts where they would be in direct contact with Covid-19. At the core of the analysis of these situations is the notion of liminal space and the realisation that time appears to have a new meaning; what we once knew as normal no longer exists, but we have yet to reach the 'new normal'.
2021-03-01T00:00:00ZTaking guidance from parents involved in a longitudinal birth cohort - the ROLO family advisory committee.Walsh, N MO'Brien, E CGeraghty, A AByrne, D FWhelan, AReilly, SMurray, SReilly, CAdams, EFarnan, P MMcAuliffe, F Mhttp://hdl.handle.net/10147/6297802021-06-24T02:05:38Z2020-04-28T00:00:00ZTaking guidance from parents involved in a longitudinal birth cohort - the ROLO family advisory committee.
Walsh, N M; O'Brien, E C; Geraghty, A A; Byrne, D F; Whelan, A; Reilly, S; Murray, S; Reilly, C; Adams, E; Farnan, P M; McAuliffe, F M
Background: The ROLO Study (Randomised cOntrol trial of a Low glycaemic index diet in pregnancy to prevent macrosomia) was a randomised control trial conducted between 2007 and 2011 to examine if a low glycaemic index (GI) diet could reduce the incidence of macrosomia. The ROLO Family Advisory Committee is a self-selected group of parents who are involved in the longitudinal follow-up of the ROLO Study. The committee was established in 2017 and the goal is to achieve a partnership between ROLO families and researchers, leading to improved research quality, relevance, and outcomes. This research method is termed "Public and patient involvement (PPI)" and describes how researchers collaborate and engage with the public in order to make research more relevant to them.
Methods: The ROLO study mothers and children have been prospectively followed-up at multiple time points post-pregnancy. In October 2017, all women were invited to join the ROLO Family Advisory Committee via email or via advertisement on the ROLO Study Facebook page. Fathers and other guardians of the study children were also invited to join. Two annual meetings with the research team and parents were held in 2018 and 2019. The meetings were recorded, transcribed verbatim by researchers, and thematically analysed.
Results: Parents provided opinions on the areas they felt should be explored within the ROLO study using information that was collected up to the current follow-up point. They also shared views on research interests which were of importance to them. These topics included; child mental health, fussy eating in childhood and healthy eating policies in schools. Mothers were much more concerned about factors which influenced their child's health rather than their own. Incorporating an element of PPI to this study was found to be a positive learning experience for participants and researchers.
Conclusion: The involvement of parents has enriched the research agenda at the UCD Perinatal Research Centre. We will continue to engage with the parents of the ROLO Study and plan to involve the children to explore their opinions at the next opportunity.
2020-04-28T00:00:00ZThe impact of diet, body composition, and physical activity on child bone mineral density at five years of age-findings from the ROLO Kids Study.McVey, Marco KGeraghty, Aisling AO'Brien, Eileen CMcKenna, Malachi JKilbane, Mark TCrowley, Rachel KTwomey, Patrick JMcAuliffe, Fionnuala Mhttp://hdl.handle.net/10147/6294382021-05-21T01:45:52Z2019-11-01T00:00:00ZThe impact of diet, body composition, and physical activity on child bone mineral density at five years of age-findings from the ROLO Kids Study.
McVey, Marco K; Geraghty, Aisling A; O'Brien, Eileen C; McKenna, Malachi J; Kilbane, Mark T; Crowley, Rachel K; Twomey, Patrick J; McAuliffe, Fionnuala M
Bone health is extremely important in early childhood because children with low bone mineral density (BMD) are at a greater risk of bone fractures. While physical activity and intake of both calcium and vitamin D benefit BMD in older children, there is limited research on the determinants of good bone health in early childhood. The aim of this cross-sectional study was to investigate the impact of diet, physical activity, and body composition on BMD at five years of age. Dietary intakes and physical activity levels were measured through questionnaires. Whole body BMD was measured by dual-energy X-ray absorptiometry in 102 children. Child weight, height, circumferences, skinfolds and serum 25-hydroxyvitamin D (25OHD) concentrations were assessed. There was no association between BMD and dietary calcium, dietary vitamin D, 25OHD, physical activity, or sedentary behaviour. Several measures of body composition were significantly positively associated with BMD; however, neither fat mass nor lean body mass was associated with BMD.Conclusion: Although we found no association between self-reported dietary and lifestyle factors and bone health in early years, increased body size was linked with higher BMD. These findings are important as identifying modifiable factors that can improve bone health at a young age is of utmost importance.What is Known:• Bone health is extremely important in early childhood, as children with low bone mineral density (BMD) are at greater risk of bone fractures.• Physical activity has been found to be beneficial for bone health in adolescents, and body composition has also been associated with BMD in teenage years.• Limited research on the determinants of good bone health in early childhood.What is New:• No association between self-reported lifestyle and dietary factors with bone health in early childhood.• Increased body size was associated with higher BMD at five years of age.
2019-11-01T00:00:00ZReproductive health outcomes in women with psoriatic arthritis.Murray, KieranMoore, LouiseMcAuliffe, FionnualaVeale, Douglas Jhttp://hdl.handle.net/10147/6271842020-02-13T02:06:17Z2019-02-15T00:00:00ZReproductive health outcomes in women with psoriatic arthritis.
Murray, Kieran; Moore, Louise; McAuliffe, Fionnuala; Veale, Douglas J
2019-02-15T00:00:00Z