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Cardiac MRI for myocardial ischemia.
Daly, Caroline Kwong, Raymond Y
Daly, Caroline
Kwong, Raymond Y
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Departments
Date
2013
Date Submitted
Keywords
DIAGNOSIS
Other Subjects
MAGNETIC RESONANCE IMAGING
MYOCARDIAL ISCHAEMIA
MYOCARDIAL ISCHAEMIA
Subject Mesh
Coronary Circulation
Coronary Vessels
Humans
Magnetic Resonance Imaging, Cine
Myocardial Ischemia
Myocardium
Coronary Vessels
Humans
Magnetic Resonance Imaging, Cine
Myocardial Ischemia
Myocardium
Planned Date
Start Date
Collaborators
Principal Investigators
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Adobe PDF, 1.95 MB
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Abstract
Proper assessment of the physiologic impact of coronary artery stenosis on the LV myocardium can affect patient prognosis and treatment decisions. Cardiac magnetic resonance imaging (CMR) assesses myocardial perfusion by imaging the myocardium during a first-pass transit of an intravenous gadolinium bolus, with spatial and temporal resolution substantially higher than nuclear myocardial perfusion imaging. Coupled with late gadolinium enhancement (LGE) imaging for infarction during the same imaging session, CMR with vasodilating stress perfusion imaging can qualitatively and quantitatively assess the myocardial extent of hypoperfusion from coronary stenosis independent of infarcted myocardium. This approach has been validated experimentally, and multiple clinical trials have established its diagnostic robustness when compared to stress single-photon emission computed tomography. In specialized centers, dobutamine stress CMR has been shown to have incremental diagnostic value above stress echocardiography due to its high imaging quality and ability to image the heart with no restriction of imaging window. This paper reviews the technical aspects, diagnostic utility, prognostic values, challenges to clinical adaptation, and future developments of stress CMR imaging.
Language
en
ISSN
1947-6108
eISSN
ISBN
DOI
PMID
24066194