Dyslipidemia therapy update: the importance of full lipid profile assessment.
Menown, I B A Murtagh, G Maher, V Cooney, M T Graham, I M Tomkin, G
Menown, I B A
Murtagh, G
Maher, V
Cooney, M T
Graham, I M
Tomkin, G
Advisors
Editors
Other Contributors
Date
2009-07
Date Submitted
Keywords
Other Subjects
Subject Mesh
Atherosclerosis
Cardiovascular Diseases
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Dyslipidemias
Humans
Practice Guidelines as Topic
Risk Assessment
Triglycerides
Cardiovascular Diseases
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
Dyslipidemias
Humans
Practice Guidelines as Topic
Risk Assessment
Triglycerides
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Lipid guidelines typically focus on total cholesterol +/- low-density lipoprotein cholesterol levels with less emphasis on high-density lipoprotein cholesterol (HDL-C) or triglyceride assessment, thus potentially underestimating cardiovascular (CV) risk and the need for lifestyle or treatment optimization. In this article, we highlight how reliance on isolated total cholesterol assessment may miss prognostically relevant lipid abnormalities; we describe from the European Systematic COronary Risk Evaluation (SCORE) data set how incorporation of HDL-C may improve estimation of CV risk; and, finally, we critically evaluate the evidence base surrounding triglycerides and CV risk.
Language
en
ISSN
0741-238X
eISSN
ISBN
DOI
10.1007/s12325-009-0052-3
PMID
19649582