Subacute cutaneous lupus erythematosus presenting as poikiloderma.
Hughes, R Loftus, B Kirby, B
Hughes, R
Loftus, B
Kirby, B
Advisors
Editors
Other Contributors
Date
2012-02-01T10:49:26Z
Date Submitted
Keywords
Other Subjects
Subject Mesh
Alopecia/*pathology
Diagnosis, Differential
Female
Humans
Lupus Erythematosus, Cutaneous/immunology/*pathology
Middle Aged
Rothmund-Thomson Syndrome/immunology/*pathology
Diagnosis, Differential
Female
Humans
Lupus Erythematosus, Cutaneous/immunology/*pathology
Middle Aged
Rothmund-Thomson Syndrome/immunology/*pathology
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Subacute cutaneous lupus erythematosus (SCLE) is a recognised variant of lupus erythematosus (LE), which accounts for 10-15% of all cases of cutaneous LE, occurring most commonly in young to middle-aged white women. Diagnosis is based on the detection of anti-Ro/SS-A antibodies in the skin and serum, characteristic clinical and histological cutaneous involvement, and relatively mild systemic involvement. Several unusual variants of SCLE have been reported including erythrodermic SCLE, SCLE with vitiligo-like lesions, acral SCLE and bullous SCLE. Poikoilodermatous SCLE is a recognised but rare variant of SCLE. There are currently only two case reports, comprising five individual cases, in the literature. We present a case of SCLE in which the main clinical findings were an extensive photodistributed poikilodermatous rash and alopecia.
Language
eng
ISSN
1365-2230 (Electronic)
0307-6938 (Linking)
0307-6938 (Linking)
eISSN
ISBN
DOI
10.1111/j.1365-2230.2009.03615.x
PMID
20055848