The impact of ultrasonographic placental architecture on antenatal course, labor and delivery in a low-risk primigravid population.
Cooley, Sharon M Donnelly, Jennifer C Walsh, Thomas McMahon, Corrina Gillan, John Geary, Michael P
Cooley, Sharon M
Donnelly, Jennifer C
Walsh, Thomas
McMahon, Corrina
Gillan, John
Geary, Michael P
Advisors
Editors
Other Contributors
Date
2011-03
Date Submitted
Keywords
Other Subjects
Subject Mesh
Adolescent
Adult
Delivery, Obstetric
Female
Fetal Growth Retardation
Gravidity
Humans
Labor, Obstetric
Placenta
Population
Pre-Eclampsia
Pregnancy
Pregnancy Outcome
Retrospective Studies
Risk Factors
Ultrasonography, Prenatal
Young Adult
Adult
Delivery, Obstetric
Female
Fetal Growth Retardation
Gravidity
Humans
Labor, Obstetric
Placenta
Population
Pre-Eclampsia
Pregnancy
Pregnancy Outcome
Retrospective Studies
Risk Factors
Ultrasonography, Prenatal
Young Adult
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
To ascertain the impact of placental architecture on antenatal course and labor delivery in a low-risk primigravid population.
This study involves prospective recruitment of 1011 low-risk primigravids with placental ultrasound at 22?24 weeks and 36 weeks. Detailed postnatal review of all mothers and infants was undertaken. Retrospective analysis of ultrasound and clinical outcome data was performed.
Eight hundred ten women with complete outcome data were available. Anterior placentation was statistically associated with intrauterine growth restriction (IUGR) and preterm birth and fundal placentation was significantly associated with a higher incidence of pregnancy-induced hypertension and infants with a birthweight less than the 9th centile. Placental infarcts in the third trimester was significantly increased in cases complicated by pre-eclampsia (PET) and in cases with fetal acidosis. Placental calcification was associated a 40-fold increase in the incidence of IUGR. Placental lakes in the second trimester were more prevalent in patients with threatened miscarriage. Increased placental thickness was associated with a higher rate of fetal acidosis. The Grannum grade of the placenta was higher with threatened first or second trimester loss, PET and in infants born less than 9th centile for gestation.
Placental site and architecture impact on the incidence of maternal and fetal disease.
This study involves prospective recruitment of 1011 low-risk primigravids with placental ultrasound at 22?24 weeks and 36 weeks. Detailed postnatal review of all mothers and infants was undertaken. Retrospective analysis of ultrasound and clinical outcome data was performed.
Eight hundred ten women with complete outcome data were available. Anterior placentation was statistically associated with intrauterine growth restriction (IUGR) and preterm birth and fundal placentation was significantly associated with a higher incidence of pregnancy-induced hypertension and infants with a birthweight less than the 9th centile. Placental infarcts in the third trimester was significantly increased in cases complicated by pre-eclampsia (PET) and in cases with fetal acidosis. Placental calcification was associated a 40-fold increase in the incidence of IUGR. Placental lakes in the second trimester were more prevalent in patients with threatened miscarriage. Increased placental thickness was associated with a higher rate of fetal acidosis. The Grannum grade of the placenta was higher with threatened first or second trimester loss, PET and in infants born less than 9th centile for gestation.
Placental site and architecture impact on the incidence of maternal and fetal disease.
Language
en
ISSN
1476-4954
eISSN
ISBN
DOI
10.3109/14767058.2010.497877
PMID
20608801