Publication

Functional dyspepsia: the role of visceral hypersensitivity in its pathogenesis.

Keohane, John
; 
Quigley, Eamonn M M
Author
Keohane, John
 Quigley, Eamonn M M
Advisors
Editors
Other Contributors
Departments
Department of Medicine, Alimentary Pharmabiotic Centre, Clinical Sciences, Building, Cork University Hospital, Cork, Ireland.
Date
2012-02-03T15:05:10Z
Date Submitted
Keywords
Other Subjects
Subject Mesh
Analgesics/pharmacology/therapeutic use
Central Nervous System/drug effects/physiopathology
Dyspepsia/drug therapy/*etiology/*physiopathology
Efferent Pathways/drug effects/physiopathology
Enteric Nervous System/drug effects/physiopathology
Food Hypersensitivity/complications/physiopathology
Gastrointestinal Tract/*innervation/*physiopathology
Helicobacter Infections/complications/physiopathology
Helicobacter pylori
Humans
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
URI
https://hdl.handle.net/10147/208843
Abstract
Functional, or non-ulcer, dyspepsia (FD) is one of the most common reasons for referral to gastroenterologists. It is associated with significant morbidity and impaired quality of life. Many authorities believe that functional dyspepsia and irritable bowel syndrome represent part of the spectrum of the same disease process. The pathophysiology of FD remains unclear but several theories have been proposed including visceral hypersensitivity, gastric motor dysfunction, Helicobacter pylori infection and psychosocial factors. In this review, we look at the evidence, to date, for the role of visceral hypersensitivity in the aetiology of FD.
Language
eng
Citation
World J Gastroenterol. 2006 May 7;12(17):2672-6.
ISSN
1007-9327 (Print)
1007-9327 (Linking)
eISSN
ISBN
DOI
PMID
16718751
PMCID
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