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Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study.
Hung, Chi-Fa Rivera, Margarita Craddock, Nick Owen, Michael J Gill, Michael Korszun, Ania Maier, Wolfgang Mors, Ole Preisig, Martin Rice, John P
Hung, Chi-Fa
Rivera, Margarita
Craddock, Nick
Owen, Michael J
Gill, Michael
Korszun, Ania
Maier, Wolfgang
Mors, Ole
Preisig, Martin
Rice, John P
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Other Contributors
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Date
2014-07
Date Submitted
Keywords
OBESITY
DEPRESSION
DEPRESSION
Other Subjects
Subject Mesh
Adult
Body Mass Index
Case-Control Studies
Depressive Disorder
Female
Genotype
Humans
Male
Mendelian Randomization Analysis
Middle Aged
Obesity
Polymorphism, Single Nucleotide
Body Mass Index
Case-Control Studies
Depressive Disorder
Female
Genotype
Humans
Male
Mendelian Randomization Analysis
Middle Aged
Obesity
Polymorphism, Single Nucleotide
Planned Date
Start Date
Collaborators
Principal Investigators
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OA Article
Adobe PDF, 372.23 KB
Alternative Titles
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Abstract
Obesity has been shown to be associated with depression and it has been suggested that higher body mass index (BMI) increases the risk of depression and other common mental disorders. However, the causal relationship remains unclear and Mendelian randomisation, a form of instrumental variable analysis, has recently been employed to attempt to resolve this issue.
Language
en
ISSN
1472-1465
eISSN
ISBN
DOI
10.1192/bjp.bp.113.130419
PMID
24809401