Chemotherapy-associated recurrent pneumothoraces in lymphangioleiomyomatosis.
Kelly, Emer Mhurchu, Elaine Ni Sukor, Sumainizah McDonnell, Timothy J Tryfonopoulos, Dimitrios Keane, Michael P
Kelly, Emer
Mhurchu, Elaine Ni
Sukor, Sumainizah
McDonnell, Timothy J
Tryfonopoulos, Dimitrios
Keane, Michael P
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Date
2012-02-01T10:33:45Z
Date Submitted
Keywords
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Subject Mesh
Antibodies, Monoclonal/adverse effects
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Breast Neoplasms/*drug therapy
Female
Humans
Lung Neoplasms/*complications/therapy
Lymphangioleiomyomatosis/*complications/therapy
Middle Aged
Neoplasms, Second Primary/*drug therapy
Oxygen Inhalation Therapy
Pneumothorax/*chemically induced/*complications
Quinazolines/adverse effects
Antibodies, Monoclonal, Humanized
Antineoplastic Combined Chemotherapy Protocols/*adverse effects
Breast Neoplasms/*drug therapy
Female
Humans
Lung Neoplasms/*complications/therapy
Lymphangioleiomyomatosis/*complications/therapy
Middle Aged
Neoplasms, Second Primary/*drug therapy
Oxygen Inhalation Therapy
Pneumothorax/*chemically induced/*complications
Quinazolines/adverse effects
Planned Date
Start Date
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Abstract
Lymphangioleiomyomatosis is a rare cause of pneumothorax in women. We present the case of a 48-year-old woman with lymphangioleiomyomatosis, who had never had a pneumothorax prior to commencing chemotherapy for breast cancer. During chemotherapy she developed 3 pneumothoraces and 2 episodes of pneumomediastinum. We suggest that the pneumothoraces were caused by the chemotherapy. To our knowledge, this is the first reported case of chemotherapy triggering pneumothoraces in a woman with lymphangioleiomyomatosis.
Language
eng
Citation
ISSN
0020-1324 (Print)
0020-1324 (Linking)
0020-1324 (Linking)
eISSN
ISBN
DOI
PMID
20979677