Cardiovascular dysfunction in infants with neonatal encephalopathy.
Armstrong, Katey Franklin, Orla Sweetman, Deirdre Molloy, Eleanor J
Armstrong, Katey
Franklin, Orla
Sweetman, Deirdre
Molloy, Eleanor J
Advisors
Editors
Other Contributors
Date
2012-04
Date Submitted
Keywords
Other Subjects
Subject Mesh
Asphyxia Neonatorum
Biological Markers
Cardiovascular Diseases
Humans
Hypothermia, Induced
Hypoxia-Ischemia, Brain
Infant, Newborn
Biological Markers
Cardiovascular Diseases
Humans
Hypothermia, Induced
Hypoxia-Ischemia, Brain
Infant, Newborn
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Severe perinatal asphyxia with hypoxic ischaemic encephalopathy occurs in approximately 1-2/1000 live births and is an important cause of cerebral palsy and associated neurological disabilities in children. Multiorgan dysfunction commonly occurs as part of the asphyxial episode, with cardiovascular dysfunction occurring in up to a third of infants. This narrative paper attempts to review the literature on the importance of early recognition of cardiac dysfunction using echocardiography and biomarkers such as troponin and brain type natriuretic peptide. These tools may allow accurate assessment of cardiac dysfunction and guide therapy to improve outcome.
Language
en
ISSN
1468-2044
eISSN
ISBN
DOI
10.1136/adc.2011.214205
PMID
21798875