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Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.
Madotto, Fabiana Rezoagli, Emanuele Pham, Tài Schmidt, Marcello McNicholas, Bairbre Protti, Alessandro Panwar, Rakshit Bellani, Giacomo Fan, Eddy van Haren, Frank
Madotto, Fabiana
Rezoagli, Emanuele
Pham, Tài
Schmidt, Marcello
McNicholas, Bairbre
Protti, Alessandro
Panwar, Rakshit
Bellani, Giacomo
Fan, Eddy
van Haren, Frank
Advisors
Editors
Other Contributors
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Date
2020-03-31
Date Submitted
Keywords
Acute respiratory distress syndrome
Hyperoxemia
Hyperoxia
Hypoxemia
HYPOXIA
Invasive mechanical ventilation
MORTALITY
Oxygen therapy
Hyperoxemia
Hyperoxia
Hypoxemia
HYPOXIA
Invasive mechanical ventilation
MORTALITY
Oxygen therapy
Other Subjects
Subject Mesh
Planned Date
Start Date
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s13054-020-2826-6.pdf
Adobe PDF, 1.47 MB
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Abstract
In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia).
Language
en
Citation
ISSN
eISSN
1466-609X
ISBN
DOI
10.1186/s13054-020-2826-6
PMID
32234077