Publication

Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method.

Johansson, Mattias
; 
Roberts, Angus
; 
Chen, Dan
; 
Li, Yaoyong
; 
Delahaye-Sourdeix, Manon
; 
Aswani, Niraj
; 
Greenwood, Mark A
; 
Benhamou, Simone
; 
Lagiou, Pagona
; 
Holcátová, Ivana
... show 10 more
Author
Johansson, Mattias
 Roberts, Angus
 Chen, Dan
 Li, Yaoyong
 Delahaye-Sourdeix, Manon
 Aswani, Niraj
 Greenwood, Mark A
 Benhamou, Simone
 Lagiou, Pagona
 Holcátová, Ivana
 Richiardi, Lorenzo
 Kjaerheim, Kristina
 Agudo, Antonio
 Castellsagué, Xavier
 Macfarlane, Tatiana V
 Barzan, Luigi
 Canova, Cristina
 Thakker, Nalin S
 Conway, David I
 Znaor, Ariana
 Healy, Claire M
 Ahrens, Wolfgang
 Zaridze, David
 Szeszenia-Dabrowska, Neonilia
 Lissowska, Jolanta
 Fabiánová, Eleonóra
 Mates, Ioan Nicolae
 Bencko, Vladimir
 Foretova, Lenka
 Janout, Vladimir
 Curado, Maria Paula
 Koifman, Sergio
 Menezes, Ana
 Wünsch-Filho, Victor
 Eluf-Neto, Jose
 Boffetta, Paolo
 Franceschi, Silvia
 Herrero, Rolando
 Fernandez Garrote, Leticia
 Talamini, Renato
 Boccia, Stefania
 Galan, Pilar
 Vatten, Lars
 Thomson, Peter
 Zelenika, Diana
 Lathrop, Mark
 Byrnes, Graham
 Cunningham, Hamish
 Brennan, Paul
 Wakefield, Jon
 McKay, James D
Advisors
Editors
Other Contributors
Departments
Section of Genetics, International Agency for Research on Cancer (IARC), Lyon, France. johanssonm@iarc.fr
Date
2012
Date Submitted
Keywords
Other Subjects
Subject Mesh
Bayes Theorem
Chromosomes, Human, Pair 4
Computational Biology
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans
Internet
Lung Neoplasms
Mouth Neoplasms
Polymorphism, Single Nucleotide
Reproducibility of Results
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
URI
https://hdl.handle.net/10147/288446
Abstract
Genome-wide association studies (GWAS) require large sample sizes to obtain adequate statistical power, but it may be possible to increase the power by incorporating complementary data. In this study we investigated the feasibility of automatically retrieving information from the medical literature and leveraging this information in GWAS.
Language
en
Citation
Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method. 2012, 7 (5):e36888 PLoS ONE
ISSN
1932-6203
eISSN
ISBN
DOI
10.1371/journal.pone.0036888
PMID
22662130
PMCID
Sponsorships
Funding Sources
Funding Amounts
Grant Identifiers
Methodology
Duration
Ethical Approval