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Smoking prolongs the infectivity of patients with tuberculosis.

Siddiqui, U A
O'Toole, M
Kabir, Z
Qureshi, S
Gibbons, N
Kane, M
Keane, J
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Date
2010-10
Date Submitted
Keywords
Other Subjects
Subject Mesh
Adult
Antitubercular Agents
Cross-Sectional Studies
Female
Humans
Male
Retrospective Studies
Smoking
Sputum
Tuberculosis, Pulmonary
Planned Date
Start Date
Collaborators
Principal Investigators
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Abstract
We sought to establish if smokers on anti-tuberculosis treatment are more likely to have a prolonged period of infectivity, compared to non-smoking tuberculosis patients, in a low tuberculosis prevalence country. We conducted a cross-sectional, retrospective study in Ireland that recruited 53 microbiologically confirmed cases of pulmonary tuberculosis (PTB). The age-sex adjusted odds ratios (AOR) suggest that the infectivity status of PTB on treatment was four times more likely to be prolonged beyond 6-8 weeks, if the cases had a smoking history (AOR: 4.42; 95% CI: 1.23; 15.9). Smoking was associated with delayed sputum smear conversion in PTB patients on treatment.
Language
en
ISSN
0332-3102
eISSN
ISBN
DOI
PMID
21186753
PMCID
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