Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage.
Dempsey, Mark Flood, Karen Burke, Naomi Fletcher, Patricia Kirkham, Colin Geary, Michael Malone, Fergal D
Dempsey, Mark
Flood, Karen
Burke, Naomi
Fletcher, Patricia
Kirkham, Colin
Geary, Michael
Malone, Fergal D
Citations
Altmetric:
Advisors
Editors
Other Contributors
Departments
Date
2014-05-14
Date Submitted
Keywords
PREGNANCY
CHILDBIRTH
CHILDBIRTH
Other Subjects
MISCARRIAGE
PERINATAL OUTCOME
PERINATAL OUTCOME
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Abstract Objective: We sought to determine subsequent pregnancy outcomes in a cohort of women with a history of unexplained RM who were not receiving medical treatment. Study Design: This was a prospective cohort study, of women with a history of three unexplained consecutive first trimester losses, who were recruited and followed in their subsequent pregnancy. Control patients were healthy pregnant patients with no previous adverse perinatal outcome. Results: A total of 42 patients with a history of unexplained RM were recruited to the study. 9 (21.4%) experienced a further first trimester miscarriage, 1 case of ectopic and 1 case of partial molar pregnancy. 74% (23/31) of the RM cohort had a vaginal delivery. There was one case of severe pre-eclampsia. The RM group delivered at a mean gestational age of 38+2 weeks and with a mean birth-weight of 3.23kg. None of the neonates were under the 10(th) centile for gestational age. Overall, there was no significant difference in pregnancy outcomes between the two cohorts. Conclusion: Our study confirms the reassuring prognosis for achieving a live birth in the unexplained RM population with a very low incidence of adverse events with the majority delivering appropriately grown fetuses at term.
Language
en
ISSN
1476-4954
eISSN
ISBN
DOI
10.3109/14767058.2014.923394
PMID
24824106