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Post-operative infection and sepsis in humans is associated with deficient gene expression of γc cytokines and their apoptosis mediators.
White, Mary ; Mahon, Vivienne ; Grealy, Robert ; Doherty, Derek G ; Stordeur, Patrick ; Kelleher, Dermot P ; McManus, Ross ; Ryan, Thomas
White, Mary
Mahon, Vivienne
Grealy, Robert
Doherty, Derek G
Stordeur, Patrick
Kelleher, Dermot P
McManus, Ross
Ryan, Thomas
Advisors
Editors
Other Contributors
Date
2011-06
Date Submitted
Keywords
Other Subjects
Subject Mesh
Aged
Aged, 80 and over
Antigens, CD3
Apoptosis Regulatory Proteins
Bacteremia
Cells, Cultured
Chemokines, C
Cohort Studies
Female
Gene Expression Regulation, Bacterial
Humans
Interferon-gamma
Interleukin-2
Interleukin-7
Lipopolysaccharides
Male
Postoperative Complications
Prospective Studies
Sepsis
Aged, 80 and over
Antigens, CD3
Apoptosis Regulatory Proteins
Bacteremia
Cells, Cultured
Chemokines, C
Cohort Studies
Female
Gene Expression Regulation, Bacterial
Humans
Interferon-gamma
Interleukin-2
Interleukin-7
Lipopolysaccharides
Male
Postoperative Complications
Prospective Studies
Sepsis
Planned Date
Start Date
Collaborators
Principal Investigators
Files
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cc10293.pdf
Adobe PDF, 1.13 MB
Alternative Titles
Publisher
Abstract
Lymphocyte homeostasis is dependent on the γc cytokines. We hypothesised that sepsis in humans is associated with differential gene expression of the γc cytokines and their associated apoptosis mediators.
Language
en
ISSN
1466-609X
eISSN
ISBN
DOI
10.1186/cc10293
PMID
21711552
