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Oral Hairy Leukoplakia in Healthy, Immunocompetent Individuals
Galvin, S Healy, CM
Galvin, S
Healy, CM
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2014-06
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DENTAL HEALTH
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Abstract
OHL, first described in 1981 and caused by the Epstein Barr Virus (EBV), presents as white, shaggy, non-removable plaques, typically on the lateral borders of the tongue 5 . It was initially considered pathognomic of HIV infection and latterly of immunosuppression. However more recently it is increasingly being reported as a complication of localised immunosuppression with topical or inhaled steroids 7-9 . Rare cases have also been documented in HIV negative individuals with no underlying history of topical or systemic immunosuppression 3,4,8,9 . It has been postulated that age may be a factor in some of these cases and chronic reactivation of EBV has been found to be related to aging 10 .
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en