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Development and validation of the food allergy severity score.
Fernández-Rivas, Montserrat Gómez García, Ismael Gonzalo-Fernández, Alejandro Fuentes Ferrer, Manuel Dölle-Bierke, Sabine Marco-Martín, Guadalupe Ballmer-Weber, Barbara K Asero, Riccardo Belohlavkova, Simona Beyer, Kirsten
Fernández-Rivas, Montserrat
Gómez García, Ismael
Gonzalo-Fernández, Alejandro
Fuentes Ferrer, Manuel
Dölle-Bierke, Sabine
Marco-Martín, Guadalupe
Ballmer-Weber, Barbara K
Asero, Riccardo
Belohlavkova, Simona
Beyer, Kirsten
Author
Fernández-Rivas, Montserrat
Gómez García, Ismael
Gonzalo-Fernández, Alejandro
Fuentes Ferrer, Manuel
Dölle-Bierke, Sabine
Marco-Martín, Guadalupe
Ballmer-Weber, Barbara K
Asero, Riccardo
Belohlavkova, Simona
Beyer, Kirsten
de Blay, Frédéric
Clausen, Michael
Datema, Mareen R
Dubakiene, Ruta
Grimshaw, Kate E C
Hoffmann-Sommergruber, Karin
Hourihane, Jonathan O'B
Jedrzejczak-Czechowicz, Monika
Knulst, André C
Kralimarkova, Tanya
Le, Thuy-My
Papadopoulos, Nikolaos G
Popov, Todor A
Poulsen, Lars K
Purohit, Ashok
Seneviratne, Suranjith L
Simpson, Angela
Sinaniotis, Atanasios
Turkalji, Mirjana
Vázquez-Cortés, Sonia
Vera-Berrios, Rosialzira N
Muraro, Antonella
Worm, Margitta
Roberts, Graham
van Ree, Ronald
Fernández-Pérez, Cristina
Turner, Paul J
Mills, Elizabeth N Clare
Gómez García, Ismael
Gonzalo-Fernández, Alejandro
Fuentes Ferrer, Manuel
Dölle-Bierke, Sabine
Marco-Martín, Guadalupe
Ballmer-Weber, Barbara K
Asero, Riccardo
Belohlavkova, Simona
Beyer, Kirsten
de Blay, Frédéric
Clausen, Michael
Datema, Mareen R
Dubakiene, Ruta
Grimshaw, Kate E C
Hoffmann-Sommergruber, Karin
Hourihane, Jonathan O'B
Jedrzejczak-Czechowicz, Monika
Knulst, André C
Kralimarkova, Tanya
Le, Thuy-My
Papadopoulos, Nikolaos G
Popov, Todor A
Poulsen, Lars K
Purohit, Ashok
Seneviratne, Suranjith L
Simpson, Angela
Sinaniotis, Atanasios
Turkalji, Mirjana
Vázquez-Cortés, Sonia
Vera-Berrios, Rosialzira N
Muraro, Antonella
Worm, Margitta
Roberts, Graham
van Ree, Ronald
Fernández-Pérez, Cristina
Turner, Paul J
Mills, Elizabeth N Clare
Advisors
Editors
Other Contributors
Departments
Date
2021-11-12
Date Submitted
Keywords
Allergic reactions
Anaphylaxis
food allergy
score
Severity
Anaphylaxis
food allergy
score
Severity
Other Subjects
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
Files
Alternative Titles
Publisher
Abstract
oFASS and nFASS map consistently, with nFASS having greater granularity. With the outcomes emergency care, adrenaline and critical medical treatment, oFASS and nFASS had a good discrimination (receiver operating characteristic area under the curve [ROC-AUC]>0.80), classification (sensitivity 0.87-0.92, specificity 0.73-0.78), and calibration. Bootstrapping over ROC-AUC showed negligible biases (1.0 × 10-6 -1.23 × 10-3 ). In external validation, nFASS performed best with higher ROC-AUC. nFASS was strongly correlated (R 0.89) to best-worst scoring of 334 expert clinicians.
Language
en
Citation
ISSN
eISSN
1398-9995
ISBN
DOI
10.1111/all.15165
PMID
34716996
PMCID
PMC9298738