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Pitfalls of the urinary albumin creatinine ratio in detection of early diabetic kidney disease
Garrahy, A Tormey, WP
Garrahy, A
Tormey, WP
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2015-04
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KIDNEY DISEASE
DIABETES MELLITUS
DIABETES MELLITUS
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Abstract
Diabetic Kidney Disease (DKD) is the leading cause of kidney disease world-wide, for which albuminuria is the currently accepted biomarker. Despite the increased use of glucose-lowering medications and renin-angiotensin-aldosterone system (RAAS) inhibitors, prevalence of DKD continues to rise in proportion to the prevalence of diabetes 1 . Development of chronic kidney disease in patients with diabetes is associated with a significant increase in morbidity and mortality as well as health care costs, even before the development of end stage renal failure (ESRF), and its onset can be clinically silent.
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en