Cardiac biomarkers in neonatal hypoxic ischaemia.
Sweetman, D Armstrong, K Murphy, J F A Molloy, E J
Sweetman, D
Armstrong, K
Murphy, J F A
Molloy, E J
Advisors
Editors
Other Contributors
Date
2012-04
Date Submitted
Keywords
Other Subjects
Subject Mesh
Biological Markers
Electrocardiography
Humans
Hypoxia-Ischemia, Brain
Infant, Newborn
Myocardial Ischemia
Natriuretic Peptide, Brain
Troponin I
Troponin T
Electrocardiography
Humans
Hypoxia-Ischemia, Brain
Infant, Newborn
Myocardial Ischemia
Natriuretic Peptide, Brain
Troponin I
Troponin T
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Following a perinatal hypoxic-ischaemic insult, term infants commonly develop cardiovascular dysfunction. Troponin-T, troponin-I and brain natriuretic peptide are sensitive indicators of myocardial compromise. The long-term effects of cardiovascular dysfunction on neurodevelopmental outcome following perinatal hypoxic ischaemia remain controversial. Follow-up studies are warranted to ensure optimal cardiac function in adulthood. CONCLUSION: Cardiac biomarkers may improve the diagnosis of myocardial injury, help guide management, estimate mortality risk and may also aid in longterm neurodevelopmental outcome prediction following neonatal hypoxic-ischaemia.
Language
en
ISSN
1651-2227
eISSN
ISBN
DOI
10.1111/j.1651-2227.2011.02539.x
PMID
22118561