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Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health.

Townsend, Liam
; 
Dyer, Adam H
; 
Naughton, Aifric
; 
Kiersey, Rachel
; 
Holden, Dean
; 
Gardiner, Mary
; 
Dowds, Joanne
; 
O'Brien, Kate
; 
Bannan, Ciaran
; 
Nadarajan, Parthiban
... show 8 more
Author
Townsend, Liam
 Dyer, Adam H
 Naughton, Aifric
 Kiersey, Rachel
 Holden, Dean
 Gardiner, Mary
 Dowds, Joanne
 O'Brien, Kate
 Bannan, Ciaran
 Nadarajan, Parthiban
 Dunne, Jean
 Martin-Loeches, Ignacio
 Fallon, Padraic G
 Bergin, Colm
 O'Farrelly, Cliona
 Cheallaigh, Cliona Ni
 Bourke, Nollaig M
 Conlon, Niall
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Date
2021-05-07
Date Submitted
Keywords
COVID-19
T cells
Ageing
FATIGUE
immune recovery
immunophenotyping
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fimmu-12-676932.pdf
Adobe PDF, 3.67 MB
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URI
https://hdl.handle.net/10147/631523
Abstract
The immunological and inflammatory changes following acute COVID-19 are hugely variable. Persistent clinical symptoms following resolution of initial infection, termed long COVID, are also hugely variable, but association with immunological changes has not been described. We investigate changing immunological parameters in convalescent COVID-19 and interrogate their potential relationships with persistent symptoms.
Language
en
Citation
ISSN
eISSN
1664-3224
ISBN
DOI
10.3389/fimmu.2021.676932
PMID
34025675
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