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PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming resistance to PD-1 blockade in hypoxic tumours.
O' Connell, Fiona MacDonald, Jamie Sheppard, Andrew D Reynolds, John V Maher, Stephen G Lynam-Lennon, Niamh Murphy, Brona Lysaght, Joanne
O' Connell, Fiona
MacDonald, Jamie
Sheppard, Andrew D
Reynolds, John V
Maher, Stephen G
Lynam-Lennon, Niamh
Murphy, Brona
Lysaght, Joanne
Advisors
Editors
Other Contributors
Departments
Date
2022-03-01
Date Submitted
Keywords
glycolysis
Bcl-xl
GLUT1
Oxidative phosphorylation
immune checkpoints
Bcl-xl
GLUT1
Oxidative phosphorylation
immune checkpoints
Other Subjects
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
Files
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main (4).pdf
Adobe PDF, 6.52 MB
Alternative Titles
Publisher
Abstract
Language
en
Citation
ISSN
1936-5233
eISSN
ISBN
DOI
10.1016/j.tranon.2022.101381
PMID
35245832
PMCID
PMC8894275