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Influenza and pneumococcal vaccination and varicella status in inflammatory arthritis patients.
McCarthy, E M de Barra, E Bergin, C Cunnane, G Doran, M
McCarthy, E M
de Barra, E
Bergin, C
Cunnane, G
Doran, M
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Editors
Other Contributors
Date
2011-11-15T16:03:56Z
Date Submitted
Keywords
Other Subjects
Subject Mesh
Adolescent
Adult
Aged
Aged, 80 and over
Arthritis, Rheumatoid
Chickenpox
Comorbidity
Female
Humans
Influenza Vaccines
Influenza, Human
Ireland
Male
Middle Aged
Pneumococcal Infections
Pneumococcal Vaccines
Questionnaires
Adult
Aged
Aged, 80 and over
Arthritis, Rheumatoid
Chickenpox
Comorbidity
Female
Humans
Influenza Vaccines
Influenza, Human
Ireland
Male
Middle Aged
Pneumococcal Infections
Pneumococcal Vaccines
Questionnaires
Planned Date
Start Date
Collaborators
Principal Investigators
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21957688.pdf
Adobe PDF, 13.79 KB
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Abstract
Patients with inflammatory arthritis are at increased risk of vaccine preventable infections. This risk is increased by immunomodulatory therapies. Vaccination for influenza and pneumococcal disease reduces the risk. Severe cases of varicella infection have occurred in patients on biologic therapies. We sought to identify vaccination rates for commonly acquired infections and to ascertain varicella immune status in patients with inflammatory arthritis. 100 patients with inflammatory arthritis were administered a standardised questionnaire. Data collected included age, diagnosis, vaccination history, history of varicella, treatment and the presence of other indications for vaccination. 58 patients (58%) had not received the influenza vaccine in the past year. Only 19 patients (19%) had ever received pneumococcal vaccine. Anti TNF use did not predict vaccination (p = .46). An increasing number of co morbid conditions predicted both pneumococcal (p < 0.003) and influenza vaccine (p < 0.03) administration. Nineteen patients (19%) gave no history of varicella infection, none having had varicella titres checked pre treatment. Immunisation rates in patients with inflammatory arthritis on immunosuppressive therapies are low. Immunisation schedules should be available for each patient during rheumatology and general practice consultations.
Language
en
ISSN
0332-3102
eISSN
ISBN
DOI
PMID
21957688