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The relationship between procedural volume and patient outcomes for percutaneous coronary interventions: a systematic review and meta-analysis.

Health Information and Quality Authority (HIQA)
Walsh, Kieran A
Plunkett, Thomas
O'Brien, Kirsty K
Teljeur, Conor
Smith, Susan M
Harrington, Patricia
Ryan, Máirín
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Date
2021-01-28
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Keywords
PCI
STEMI
systematic review
health services research
HEART ATTACK
meta-analysis
myocardial infarction.
volume-outcome
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Abstract
Of 1,154 unique records retrieved, 22 observational studies with 6,432,265 patients were included. No significant association was found between total PCI hospital volume and mortality (odds ratio [OR]: 0.84, 95% confidence interval [CI]: 0.69-1.03, I 2 = 86%). A temporal trend from significant to non-significant pooled effect estimates was observed. The pooled effect estimate for mortality was found to be significantly in favour of high-volume operators for total PCI procedures (OR: 0.77, 95% CI: 0.63-0.94, I 2 = 93%), and for high-volume hospitals for primary PCI procedures (OR: 0.77, 95% CI: 0.62-0.94, I 2 = 78%). Overall, GRADE certainty of evidence was 'very low'. There were mixed findings for secondary outcomes.
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en
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2515-4826
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DOI
10.12688/hrbopenres.13203.1
PMID
33842830
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