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Thyroid disorders in girls with Turner syndrome and the influence of the underlying karyotype.
Nadeem, M ; Roche, E F
Nadeem, M
Roche, E F
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Date
2015-03
Date Submitted
Keywords
THYROID DISORDER
TURNER SYNDROME
TURNER SYNDROME
Other Subjects
Subject Mesh
Adolescent
Female
Humans
Ireland
Karyotyping
Prevalence
Statistics as Topic
Thyroid Diseases
Thyroid Function Tests
Turner Syndrome
Female
Humans
Ireland
Karyotyping
Prevalence
Statistics as Topic
Thyroid Diseases
Thyroid Function Tests
Turner Syndrome
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
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Abstract
The risk of developing thyroid dysfunction is higher in Turner syndrome (TS) than the general population 1,2 . In previous studies, the influence of karyotype 3 and thyroid autoantibodies 4 on thyroid disorder in patients with TS has been investigated. We therefore set out to determine the prevalence of thyroid dysfunction in Irish girls with TS. The impact of underlying karyotype and thyroid autoantibodies has also been examined. The presence of thyroid dysfunction was assessed by measuring serum thyroid-stimulating hormone (TSH), thyroxin (T4) and anti-thyroid peroxidase antibodies (TPO-Ab) values. The association between TPO-Ab values and thyroid dysfunction (hypothyroidism and hyperthyroidism) was also assessed.
Language
en
ISSN
0332-3102
eISSN
ISBN
DOI
PMID
25876307
