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Beta-Hemolytic Streptococcal Infective Endocarditis: Characteristics and Outcomes From a Large, Multinational Cohort.
Fernández Hidalgo, Núria Gharamti, Amal A Aznar, María Luisa Almirante, Benito Yasmin, Mohamad Fortes, Claudio Querido Plesiat, Patrick Doco-Lecompte, Thanh Rizk, Hussein Wray, Dannah
Fernández Hidalgo, Núria
Gharamti, Amal A
Aznar, María Luisa
Almirante, Benito
Yasmin, Mohamad
Fortes, Claudio Querido
Plesiat, Patrick
Doco-Lecompte, Thanh
Rizk, Hussein
Wray, Dannah
Author
Fernández Hidalgo, Núria
Gharamti, Amal A
Aznar, María Luisa
Almirante, Benito
Yasmin, Mohamad
Fortes, Claudio Querido
Plesiat, Patrick
Doco-Lecompte, Thanh
Rizk, Hussein
Wray, Dannah
Lamas, Cristiane
Durante-Mangoni, Emanuele
Tattevin, Pierre
Snygg-Martin, Ulrika
Hannan, Margaret M
Chu, Vivian H
Kanafani, Zeina A
Gharamti, Amal A
Aznar, María Luisa
Almirante, Benito
Yasmin, Mohamad
Fortes, Claudio Querido
Plesiat, Patrick
Doco-Lecompte, Thanh
Rizk, Hussein
Wray, Dannah
Lamas, Cristiane
Durante-Mangoni, Emanuele
Tattevin, Pierre
Snygg-Martin, Ulrika
Hannan, Margaret M
Chu, Vivian H
Kanafani, Zeina A
Advisors
Editors
Other Contributors
Departments
Date
2020-04-10
Date Submitted
Keywords
International Collaboration on Endocarditis
beta-hemolytic streptococci
cardiac devices
congestive heart failure
infective endocarditis
beta-hemolytic streptococci
cardiac devices
congestive heart failure
infective endocarditis
Other Subjects
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
Files
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ofaa120.pdf
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Alternative Titles
Publisher
Abstract
Among 1336 definite cases of streptococcal IE, 823 were caused by VGS and 147 by BHS. Patients with BHS IE had a lower prevalence of native valve (P < .005) and congenital heart disease predisposition (P = .002), but higher prevalence of implantable cardiac device predisposition (P < .005). Clinically, they were more likely to present acutely (P < .005) and with fever (P = .024). BHS IE was more likely to be complicated by stroke and other systemic emboli (P < .005). The overall in-hospital mortality of BHS IE was significantly higher than that of VGS IE (P = .001). In univariate analysis, variables associated with in-hospital mortality for BHS IE were age (odds ratio [OR], 1.044; P = .004), prosthetic valve IE (OR, 3.029; P = .022), congestive heart failure (OR, 2.513; P = .034), and stroke (OR, 3.198; P = .009).
Language
en
Citation
ISSN
2328-8957
eISSN
ISBN
DOI
10.1093/ofid/ofaa120
PMID
32462042