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Efficacy of paracetamol on patent ductus arteriosus closure may be dose dependent: evidence from human and murine studies.

El-Khuffash, Afif
Jain, Amish
Corcoran, David
Shah, Prakesh S
Hooper, Christopher W
Brown, Naoko
Poole, Stanley D
Shelton, Elaine L
Milne, Ginger L
Reese, Jeff
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Date
2014-09
Date Submitted
Keywords
ANALGESIC
NEONATE
Other Subjects
PATENT DUCTUS ARTERIOSUS
HEART DEFECTS, CONGENITAL
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Abstract
We evaluated the clinical effectiveness of variable courses of paracetamol on patent ductus arteriosus (PDA) closure and examined its effect on the in vitro term and preterm murine ductus arteriosus (DA).
Language
en
ISSN
1530-0447
eISSN
ISBN
DOI
10.1038/pr.2014.82
PMID
24941212
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