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Moderate-intensity aerobic and resistance exercise is safe and favorably influences body composition in patients with quiescent Inflammatory Bowel Disease: a randomized controlled cross-over trial.
Cronin, Owen Barton, Wiley Moran, Carthage Sheehan, Donal Whiston, Ronan Nugent, Helena McCarthy, Yvonne Molloy, Catherine B O'Sullivan, Orla Cotter, Paul D
Cronin, Owen
Barton, Wiley
Moran, Carthage
Sheehan, Donal
Whiston, Ronan
Nugent, Helena
McCarthy, Yvonne
Molloy, Catherine B
O'Sullivan, Orla
Cotter, Paul D
Advisors
Editors
Other Contributors
Departments
Date
2019-02-12
Date Submitted
Keywords
Body composition
Clinical trials
Exercise
Microbiome
INFLAMMATORY BOWEL DISEASE
PHYSICAL ACTIVITY
Clinical trials
Exercise
Microbiome
INFLAMMATORY BOWEL DISEASE
PHYSICAL ACTIVITY
Other Subjects
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
Files
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s12876-019-0952-x.pdf
Adobe PDF, 1.59 MB
Alternative Titles
Publisher
Abstract
Improved physical fitness was demonstrated in the exercise group by increases in median estimated VO2max (Baseline: 43.41mls/kg/min; post-intervention: 46.01mls/kg/min; pā=ā0.03). Improvement in body composition was achieved by the intervention group (nā=ā13) with a median decrease of 2.1% body fat compared with a non-exercising group (nā=ā7) (0.1% increase; pā=ā0.022). Lean tissue mass increased by a median of 1.59ākg and fat mass decreased by a median of 1.52ākg in the exercising group. No patients experienced a deterioration in disease activity scores during the exercise intervention. No clinically significant alterations in the Ī±- and Ī²-diversity of gut microbiota and associated metabolic pathways were evident.
Language
en
Citation
ISSN
eISSN
1471-230X
ISBN
DOI
10.1186/s12876-019-0952-x
PMID
30755154