Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria.

Hdl Handle:
http://hdl.handle.net/10147/620778
Title:
Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria.
Authors:
Cooper, Janine A; Moriarty, Frank; Ryan, Cristín; Smith, Susan M; Bennett, Kathleen; Fahey, Tom; Wallace, Emma; Cahir, Caitriona; Williams, David; Teeling, Mary; Hughes, Carmel M
Citation:
Potentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria. 2016: Eur. J. Clin. Pharmacol.
Publisher:
Springer
Journal:
European journal of clinical pharmacology
Issue Date:
28-Jan-2016
URI:
http://hdl.handle.net/10147/620778
DOI:
10.1007/s00228-015-2003-z
PubMed ID:
26820292
Abstract:
The purpose of this study is to establish the prevalence of potentially inappropriate prescribing (PIP) in middle-aged adults (45-64 years) in two populations with differing socio-economic profiles, and to investigate factors associated with PIP, using the PROMPT (PRescribing Optimally in Middle-aged People's Treatments) criteria.; A retrospective cross-sectional study was conducted using 2012 data from the Enhanced Prescribing Database (EPD), covering the full population in Northern Ireland and the Health Services Executive Primary Care Reimbursement Service (HSE-PCRS) database, covering the most socio-economically deprived third of the population in this age group in the Republic of Ireland. The prevalence for each PROMPT criterion and overall prevalence of PIP were calculated. Logistic regression was used to investigate the association between PIP and gender, age group and polypharmacy.; This study included 441,925 patients from the EPD and 309,748 patients from the HSE-PCRS database. Polypharmacy was common in both datasets (46.7 % in the HSE-PCRS and 20.3 % in the EPD). The prevalence of PIP was 42.9 % (95%CI 42.7, 43.1) in the HSE-PCRS and 21.1 % (95%CI 21.0, 21.2) in the EPD. Age group, female gender and polypharmacy were significantly associated with PIP in both populations (p < 0.05) and polypharmacy had the strongest association.; PIP is common amongst middle-aged people with the risk of PIP increasing with polypharmacy. Differences in the prevalence of polypharmacy and PIP between the two populations may relate to heterogeneity in healthcare services and different socio-economic profiles, with higher rates of multimorbidity and associated polypharmacy in more deprived groups.
Item Type:
Article
Language:
en
Description:
Purpose The purpose of this study is to establish the prevalence of potentially inappropriate prescribing (PIP) in middle-aged adults (45–64 years) in two populations with differing socio-economic profiles, and to investigate factors associated with PIP, using the PROMPT (PRescribing Optimally in Middle-aged People’s Treatments) criteria. Methods A retrospective cross-sectional study was conducted using 2012 data from the Enhanced Prescribing Database (EPD), covering the full population in Northern Ireland and the Health Services Executive Primary Care Reimbursement
Keywords:
PRESCRIBING
ISSN:
1432-1041

Full metadata record

DC FieldValue Language
dc.contributor.authorCooper, Janine Aen
dc.contributor.authorMoriarty, Franken
dc.contributor.authorRyan, Cristínen
dc.contributor.authorSmith, Susan Men
dc.contributor.authorBennett, Kathleenen
dc.contributor.authorFahey, Tomen
dc.contributor.authorWallace, Emmaen
dc.contributor.authorCahir, Caitrionaen
dc.contributor.authorWilliams, Daviden
dc.contributor.authorTeeling, Maryen
dc.contributor.authorHughes, Carmel Men
dc.date.accessioned2016-09-30T10:58:10Z-
dc.date.available2016-09-30T10:58:10Z-
dc.date.issued2016-01-28-
dc.identifier.citationPotentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria. 2016: Eur. J. Clin. Pharmacol.en
dc.identifier.issn1432-1041-
dc.identifier.pmid26820292-
dc.identifier.doi10.1007/s00228-015-2003-z-
dc.identifier.urihttp://hdl.handle.net/10147/620778-
dc.descriptionPurpose The purpose of this study is to establish the prevalence of potentially inappropriate prescribing (PIP) in middle-aged adults (45–64 years) in two populations with differing socio-economic profiles, and to investigate factors associated with PIP, using the PROMPT (PRescribing Optimally in Middle-aged People’s Treatments) criteria. Methods A retrospective cross-sectional study was conducted using 2012 data from the Enhanced Prescribing Database (EPD), covering the full population in Northern Ireland and the Health Services Executive Primary Care Reimbursementen
dc.description.abstractThe purpose of this study is to establish the prevalence of potentially inappropriate prescribing (PIP) in middle-aged adults (45-64 years) in two populations with differing socio-economic profiles, and to investigate factors associated with PIP, using the PROMPT (PRescribing Optimally in Middle-aged People's Treatments) criteria.en
dc.description.abstractA retrospective cross-sectional study was conducted using 2012 data from the Enhanced Prescribing Database (EPD), covering the full population in Northern Ireland and the Health Services Executive Primary Care Reimbursement Service (HSE-PCRS) database, covering the most socio-economically deprived third of the population in this age group in the Republic of Ireland. The prevalence for each PROMPT criterion and overall prevalence of PIP were calculated. Logistic regression was used to investigate the association between PIP and gender, age group and polypharmacy.en
dc.description.abstractThis study included 441,925 patients from the EPD and 309,748 patients from the HSE-PCRS database. Polypharmacy was common in both datasets (46.7 % in the HSE-PCRS and 20.3 % in the EPD). The prevalence of PIP was 42.9 % (95%CI 42.7, 43.1) in the HSE-PCRS and 21.1 % (95%CI 21.0, 21.2) in the EPD. Age group, female gender and polypharmacy were significantly associated with PIP in both populations (p < 0.05) and polypharmacy had the strongest association.en
dc.description.abstractPIP is common amongst middle-aged people with the risk of PIP increasing with polypharmacy. Differences in the prevalence of polypharmacy and PIP between the two populations may relate to heterogeneity in healthcare services and different socio-economic profiles, with higher rates of multimorbidity and associated polypharmacy in more deprived groups.en
dc.languageENGen
dc.language.isoenen
dc.publisherSpringeren
dc.rightsArchived with thanks to European journal of clinical pharmacologyen
dc.subjectPRESCRIBING-
dc.titlePotentially inappropriate prescribing in two populations with differing socio-economic profiles: a cross-sectional database study using the PROMPT criteria.en
dc.typeArticleen
dc.identifier.journalEuropean journal of clinical pharmacologyen

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