Mycobacterium avium complex pulmonary disease: characteristics and treatment in an Irish patient cohort.

Hdl Handle:
http://hdl.handle.net/10147/620585
Title:
Mycobacterium avium complex pulmonary disease: characteristics and treatment in an Irish patient cohort.
Authors:
Judge, EP; Ahmed, M; Fitzgibbon, M; McLaughlin, AM; Keane, J
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Apr-2016
URI:
http://hdl.handle.net/10147/620585
Abstract:
The prevalence of Mycobacterium avium complex (MAC) pulmonary disease is increasing globally. However, reliable national and international data relating to its epidemiology and management is lacking. During the period 2003-2014, MAC was isolated from the pulmonary samples of 75 patients at the Irish Mycobacteria Reference Laboratory (IMRL). Most patients (42, 56%) had underlying pulmonary disease, and 37 (49%) had clinical/radiographic characteristics consistent with MAC pulmonary disease. However, only 18 patients (24%) fulfilled internationally accepted criteria for diagnosis/treatment of this disease. Treatment was started in 13 (72%) of these cases, which is similar to internationally published treatment rates. The diagnosis of significant MAC pulmonary disease can be difficult, and treatment is not always warranted even when diagnostic criteria are met.
Item Type:
Article
Language:
en
Keywords:
PULMONARY DISORDER

Full metadata record

DC FieldValue Language
dc.contributor.authorJudge, EPen
dc.contributor.authorAhmed, Men
dc.contributor.authorFitzgibbon, Men
dc.contributor.authorMcLaughlin, AMen
dc.contributor.authorKeane, Jen
dc.date.accessioned2016-09-21T10:55:51Z-
dc.date.available2016-09-21T10:55:51Z-
dc.date.issued2016-04-
dc.identifier.urihttp://hdl.handle.net/10147/620585-
dc.description.abstractThe prevalence of Mycobacterium avium complex (MAC) pulmonary disease is increasing globally. However, reliable national and international data relating to its epidemiology and management is lacking. During the period 2003-2014, MAC was isolated from the pulmonary samples of 75 patients at the Irish Mycobacteria Reference Laboratory (IMRL). Most patients (42, 56%) had underlying pulmonary disease, and 37 (49%) had clinical/radiographic characteristics consistent with MAC pulmonary disease. However, only 18 patients (24%) fulfilled internationally accepted criteria for diagnosis/treatment of this disease. Treatment was started in 13 (72%) of these cases, which is similar to internationally published treatment rates. The diagnosis of significant MAC pulmonary disease can be difficult, and treatment is not always warranted even when diagnostic criteria are met.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectPULMONARY DISORDERen
dc.titleMycobacterium avium complex pulmonary disease: characteristics and treatment in an Irish patient cohort.en
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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