Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?

Hdl Handle:
http://hdl.handle.net/10147/620144
Title:
Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?
Authors:
O'Caoimh, Rónán; Gao, Yang; Gallagher, Paul Francis; Eustace, Joesph; McGlade, Ciara; Molloy, D William
Citation:
Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia? 2013, 42 (3):324-30 Age Ageing
Publisher:
Age and ageing
Journal:
Age and ageing
Issue Date:
May-2013
URI:
http://hdl.handle.net/10147/620144
DOI:
10.1093/ageing/aft044
PubMed ID:
23612864
Abstract:
the Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementia.; the objective was to determine the contribution each subtest of the Qmci makes, to its sensitivity and specificity in differentiating MCI from NC and dementia, to refine and shorten the instrument.; existing data from our previous study of 965 subjects, testing the Qmci, was analysed to compare the sensitivity and specificity of the Qmci subtests.; all the subtests of the Qmci differentiated MCI from NC. Logical memory (LM) performed the best (area under the receiver operating curve of 0.80), registration the worst, (0.56). LM and verbal fluency had the largest median differences (expressed as percentage of total score) between MCI and NC, 20 and 25%, respectively. Other subtests did not have clinically useful differences. LM was best at differentiating MCI from NC, irrespective of age or educational status.; the Qmci incorporates several important cognitive domains making it useful across the spectrum of cognitive impairment. LM is the best performing subtest for differentiating MCI from NC.
Item Type:
Article
Language:
en
Description:
the Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementia
MeSH:
Aged; Area Under Curve; Case-Control Studies; Chi-Square Distribution; Cognition; Dementia; Diagnosis, Differential; Executive Function; Female; Humans; Male; Memory; Mild Cognitive Impairment; Neuropsychological Tests; Predictive Value of Tests; Psychomotor Performance; ROC Curve
ISSN:
1468-2834

Full metadata record

DC FieldValue Language
dc.contributor.authorO'Caoimh, Rónánen
dc.contributor.authorGao, Yangen
dc.contributor.authorGallagher, Paul Francisen
dc.contributor.authorEustace, Joesphen
dc.contributor.authorMcGlade, Ciaraen
dc.contributor.authorMolloy, D Williamen
dc.date.accessioned2016-09-15T10:33:48Z-
dc.date.available2016-09-15T10:33:48Z-
dc.date.issued2013-05en
dc.identifier.citationWhich part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia? 2013, 42 (3):324-30 Age Ageingen
dc.identifier.issn1468-2834en
dc.identifier.pmid23612864en
dc.identifier.doi10.1093/ageing/aft044en
dc.identifier.urihttp://hdl.handle.net/10147/620144-
dc.descriptionthe Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementiaen
dc.description.abstractthe Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementia.en
dc.description.abstractthe objective was to determine the contribution each subtest of the Qmci makes, to its sensitivity and specificity in differentiating MCI from NC and dementia, to refine and shorten the instrument.en
dc.description.abstractexisting data from our previous study of 965 subjects, testing the Qmci, was analysed to compare the sensitivity and specificity of the Qmci subtests.en
dc.description.abstractall the subtests of the Qmci differentiated MCI from NC. Logical memory (LM) performed the best (area under the receiver operating curve of 0.80), registration the worst, (0.56). LM and verbal fluency had the largest median differences (expressed as percentage of total score) between MCI and NC, 20 and 25%, respectively. Other subtests did not have clinically useful differences. LM was best at differentiating MCI from NC, irrespective of age or educational status.en
dc.description.abstractthe Qmci incorporates several important cognitive domains making it useful across the spectrum of cognitive impairment. LM is the best performing subtest for differentiating MCI from NC.en
dc.language.isoenen
dc.publisherAge and ageingen
dc.rightsArchived with thanks to Age and ageingen
dc.subject.meshAgeden
dc.subject.meshArea Under Curveen
dc.subject.meshCase-Control Studiesen
dc.subject.meshChi-Square Distributionen
dc.subject.meshCognitionen
dc.subject.meshDementiaen
dc.subject.meshDiagnosis, Differentialen
dc.subject.meshExecutive Functionen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMemoryen
dc.subject.meshMild Cognitive Impairmenten
dc.subject.meshNeuropsychological Testsen
dc.subject.meshPredictive Value of Testsen
dc.subject.meshPsychomotor Performanceen
dc.subject.meshROC Curveen
dc.titleWhich part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?en
dc.typeArticleen
dc.identifier.journalAge and ageingen

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