Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.

Hdl Handle:
http://hdl.handle.net/10147/605742
Title:
Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.
Authors:
Nichol, Alistair; French, Craig; Little, Lorraine; Presneill, Jeffrey; Cooper, D James; Haddad, Samir; Duranteau, Jacques; Huet, Olivier; Skrifvars, Markus; Arabi, Yaseen; Bellomo, Rinaldo
Citation:
Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial. 2015, 16:39 Trials
Journal:
Trials
Issue Date:
8-Feb-2015
URI:
http://hdl.handle.net/10147/605742
DOI:
10.1186/s13063-014-0528-6
PubMed ID:
25884605
Additional Links:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326467/pdf/13063_2014_Article_528.pdf
Abstract:
Traumatic brain injury is a leading cause of death and disability worldwide. Laboratory and clinical studies demonstrate a possible beneficial effect of erythropoietin in improving outcomes in the traumatic brain injury cohort. However, there are concerns regarding the association of erythropoietin and thrombosis in the critically ill. A large-scale, multi-centre, blinded, parallel-group, placebo-controlled, randomised trial is currently underway to address this hypothesis.
Item Type:
Article
Language:
en
Keywords:
BRAIN INJURY
MeSH:
Adolescent; Adult; Aged; Brain Injuries; Clinical Protocols; Data Interpretation, Statistical; Erythropoietin; Humans; Middle Aged; Outcome Assessment (Health Care); Sample Size; Thromboembolism; Ultrasonography, Doppler
ISSN:
1745-6215

Full metadata record

DC FieldValue Language
dc.contributor.authorNichol, Alistairen
dc.contributor.authorFrench, Craigen
dc.contributor.authorLittle, Lorraineen
dc.contributor.authorPresneill, Jeffreyen
dc.contributor.authorCooper, D Jamesen
dc.contributor.authorHaddad, Samiren
dc.contributor.authorDuranteau, Jacquesen
dc.contributor.authorHuet, Olivieren
dc.contributor.authorSkrifvars, Markusen
dc.contributor.authorArabi, Yaseenen
dc.contributor.authorBellomo, Rinaldoen
dc.date.accessioned2016-04-18T14:05:14Zen
dc.date.available2016-04-18T14:05:14Zen
dc.date.issued2015-02-08en
dc.identifier.citationErythropoietin in traumatic brain injury: study protocol for a randomised controlled trial. 2015, 16:39 Trialsen
dc.identifier.issn1745-6215en
dc.identifier.pmid25884605en
dc.identifier.doi10.1186/s13063-014-0528-6en
dc.identifier.urihttp://hdl.handle.net/10147/605742en
dc.description.abstractTraumatic brain injury is a leading cause of death and disability worldwide. Laboratory and clinical studies demonstrate a possible beneficial effect of erythropoietin in improving outcomes in the traumatic brain injury cohort. However, there are concerns regarding the association of erythropoietin and thrombosis in the critically ill. A large-scale, multi-centre, blinded, parallel-group, placebo-controlled, randomised trial is currently underway to address this hypothesis.en
dc.language.isoenen
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326467/pdf/13063_2014_Article_528.pdfen
dc.rightsArchived with thanks to Trialsen
dc.subjectBRAIN INJURYen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshBrain Injuriesen
dc.subject.meshClinical Protocolsen
dc.subject.meshData Interpretation, Statisticalen
dc.subject.meshErythropoietinen
dc.subject.meshHumansen
dc.subject.meshMiddle Ageden
dc.subject.meshOutcome Assessment (Health Care)en
dc.subject.meshSample Sizeen
dc.subject.meshThromboembolismen
dc.subject.meshUltrasonography, Doppleren
dc.titleErythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.en
dc.typeArticleen
dc.identifier.journalTrialsen
dc.description.fundingOtheren
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen

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