Gentamicin dosing in therapeutic hypothermia; a quality improvement initiative

Hdl Handle:
http://hdl.handle.net/10147/596650
Title:
Gentamicin dosing in therapeutic hypothermia; a quality improvement initiative
Authors:
Whitla, L; Fitzgerald, D; Twomey, A; Knowles, S; Murphy, JFA
Publisher:
Irish Medical Journal
Journal:
Irish Medical Journal
Issue Date:
Jan-2016
URI:
http://hdl.handle.net/10147/596650
Abstract:
We read with interest a number of articles on gentamicin dosing in neonates treated with therapeutic hypothermia 1-3 . Therapeutic hypothermia has now become the standard of care for newborn infants with hypoxic-ischaemic encephalopathy. Many of these infants concurrently receive gentamicin. Gentamicin is nephrotoxic and ototoxic at high serum concentrations. We therefore carried out a study in The National Maternity Hospital Holles St to analyse trough and peak gentamicin levels in infants who were cooled and compared them to a control group of non-cooled infants.
Item Type:
Article
Language:
en
Keywords:
PREGNANCY; NEONATE; HYPOTHERMIA

Full metadata record

DC FieldValue Language
dc.contributor.authorWhitla, Len
dc.contributor.authorFitzgerald, Den
dc.contributor.authorTwomey, Aen
dc.contributor.authorKnowles, Sen
dc.contributor.authorMurphy, JFAen
dc.date.accessioned2016-02-18T15:40:47Zen
dc.date.available2016-02-18T15:40:47Zen
dc.date.issued2016-01en
dc.identifier.urihttp://hdl.handle.net/10147/596650en
dc.description.abstractWe read with interest a number of articles on gentamicin dosing in neonates treated with therapeutic hypothermia 1-3 . Therapeutic hypothermia has now become the standard of care for newborn infants with hypoxic-ischaemic encephalopathy. Many of these infants concurrently receive gentamicin. Gentamicin is nephrotoxic and ototoxic at high serum concentrations. We therefore carried out a study in The National Maternity Hospital Holles St to analyse trough and peak gentamicin levels in infants who were cooled and compared them to a control group of non-cooled infants.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.subjectPREGNANCYen
dc.subjectNEONATEen
dc.subjectHYPOTHERMIAen
dc.titleGentamicin dosing in therapeutic hypothermia; a quality improvement initiativeen
dc.typeArticleen
dc.identifier.journalIrish Medical Journalen
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
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