Technological progress in radiation therapy for brain tumors

Hdl Handle:
http://hdl.handle.net/10147/583467
Title:
Technological progress in radiation therapy for brain tumors
Authors:
Vernimmen, Frederik Jozef; Rock, Kathy
Citation:
Technological Progress in Radiation Therapy for Brain Tumors 2014, 05 (01):38 Journal of Cancer Therapy
Publisher:
Journal of Cancer Therapy
Journal:
Journal of Cancer Therapy
Issue Date:
Jan-2014
URI:
http://hdl.handle.net/10147/583467
DOI:
10.4236/jct.2014.51005
Additional Links:
http://www.scirp.org/journal/PaperDownload.aspx?DOI=10.4236/jct.2014.51005
Abstract:
To achieve a good therapeutic ratio the radiation dose to the tumor should be as high as possible with the lowest possible dose to the surrounding normal tissue. This is especially the case for brain tumors. Technological ad- vancements in diagnostic imaging, dose calculations, and radiation delivery systems, combined with a better un- derstanding of the pathophysiology of brain tumors have led to improvements in the therapeutic results. The widely used technology of delivering 3-D conformal therapy with photon beams (gamma rays) produced by Li-near Accelerators has progressed into the use of Intensity modulated radiation therapy (IMRT). Particle beams have been used for several decades for radiotherapy because of their favorable depth dose characteristics. The introduction of clinically dedicated proton beam therapy facilities has improved the access for cancer patients to this treatment. Proton therapy is of particular interest for pediatric malignancies. These technical improvements are further enhanced by the evolution in tumor physiology imaging which allows for improved delineation of the tumor. This in turn opens the potential to adjust the radiation dose to maximize the radiobiological effects. The advances in both imaging and radiation therapy delivery will be discussed.
Item Type:
Article
Language:
en
Keywords:
CANCER; BRAIN; RADIOTHERAPY
ISSN:
2151-1934; 2151-1942

Full metadata record

DC FieldValue Language
dc.contributor.authorVernimmen, Frederik Jozefen
dc.contributor.authorRock, Kathyen
dc.date.accessioned2015-12-09T10:46:56Zen
dc.date.available2015-12-09T10:46:56Zen
dc.date.issued2014-01en
dc.identifier.citationTechnological Progress in Radiation Therapy for Brain Tumors 2014, 05 (01):38 Journal of Cancer Therapyen
dc.identifier.issn2151-1934en
dc.identifier.issn2151-1942en
dc.identifier.doi10.4236/jct.2014.51005en
dc.identifier.urihttp://hdl.handle.net/10147/583467en
dc.description.abstractTo achieve a good therapeutic ratio the radiation dose to the tumor should be as high as possible with the lowest possible dose to the surrounding normal tissue. This is especially the case for brain tumors. Technological ad- vancements in diagnostic imaging, dose calculations, and radiation delivery systems, combined with a better un- derstanding of the pathophysiology of brain tumors have led to improvements in the therapeutic results. The widely used technology of delivering 3-D conformal therapy with photon beams (gamma rays) produced by Li-near Accelerators has progressed into the use of Intensity modulated radiation therapy (IMRT). Particle beams have been used for several decades for radiotherapy because of their favorable depth dose characteristics. The introduction of clinically dedicated proton beam therapy facilities has improved the access for cancer patients to this treatment. Proton therapy is of particular interest for pediatric malignancies. These technical improvements are further enhanced by the evolution in tumor physiology imaging which allows for improved delineation of the tumor. This in turn opens the potential to adjust the radiation dose to maximize the radiobiological effects. The advances in both imaging and radiation therapy delivery will be discussed.en
dc.language.isoenen
dc.publisherJournal of Cancer Therapyen
dc.relation.urlhttp://www.scirp.org/journal/PaperDownload.aspx?DOI=10.4236/jct.2014.51005en
dc.rightsArchived with thanks to Journal of Cancer Therapyen
dc.subjectCANCERen
dc.subjectBRAINen
dc.subjectRADIOTHERAPYen
dc.titleTechnological progress in radiation therapy for brain tumorsen
dc.typeArticleen
dc.identifier.journalJournal of Cancer Therapyen
dc.description.fundingNo fundingen
dc.description.provinceMunsteren
dc.description.peer-reviewpeer-reviewen
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