Diabetic retinopathy in pregnancy: a population-based study of women with pregestational diabetes.

Hdl Handle:
http://hdl.handle.net/10147/583456
Title:
Diabetic retinopathy in pregnancy: a population-based study of women with pregestational diabetes.
Authors:
Egan, Aoife M; McVicker, Lyle; Heerey, Adrienne; Carmody, Louise; Harney, Fiona; Dunne, Fidelma P
Citation:
Diabetic retinopathy in pregnancy: a population-based study of women with pregestational diabetes. 2015, 2015:310239 J Diabetes Res
Publisher:
Journal of diabetes research
Journal:
Journal of diabetes research
Issue Date:
Apr-2015
URI:
http://hdl.handle.net/10147/583456
DOI:
10.1155/2015/310239
PubMed ID:
25945354
Abstract:
The aim of this observational study was to evaluate screening and progression of diabetic retinopathy during pregnancy in women with pregestational diabetes attending five antenatal centres along the Irish Atlantic seaboard. An adequate frequency of screening was defined as at least two retinal evaluations in separate trimesters. Progression was defined as at least one stage of deterioration of diabetic retinopathy and/or development of diabetic macular edema on at least one eye. Women with pregestational diabetes who delivered after 22 gestational weeks (n = 307) were included. In total, 185 (60.3%) had an adequate number of retinal examinations. Attendance at prepregnancy care was associated with receiving adequate screening (odds ratio 6.23; CI 3.39-11.46 (P < 0.001)). Among those who received adequate evaluations (n = 185), 48 (25.9%) had retinopathy progression. Increasing booking systolic blood pressure (OR 1.03, CI 1.01-1.06, P = 0.02) and greater drop in HbA1c between first and third trimesters of pregnancy (OR 2.05, CI 1.09-3.87, P = 0.03) significantly increased the odds of progression. A significant proportion of women continue to demonstrate retinopathy progression during pregnancy. This study highlights the role of prepregnancy care and the importance of close monitoring during pregnancy and identifies those patients at the highest risk for retinopathy progression.
Item Type:
Article
Language:
en
Keywords:
DIABETES MELLITUS; PREGNANCY; EYE DISORDERS
ISSN:
2314-6753

Full metadata record

DC FieldValue Language
dc.contributor.authorEgan, Aoife Men
dc.contributor.authorMcVicker, Lyleen
dc.contributor.authorHeerey, Adrienneen
dc.contributor.authorCarmody, Louiseen
dc.contributor.authorHarney, Fionaen
dc.contributor.authorDunne, Fidelma Pen
dc.date.accessioned2015-12-09T09:44:45Zen
dc.date.available2015-12-09T09:44:45Zen
dc.date.issued2015-04en
dc.identifier.citationDiabetic retinopathy in pregnancy: a population-based study of women with pregestational diabetes. 2015, 2015:310239 J Diabetes Resen
dc.identifier.issn2314-6753en
dc.identifier.pmid25945354en
dc.identifier.doi10.1155/2015/310239en
dc.identifier.urihttp://hdl.handle.net/10147/583456en
dc.description.abstractThe aim of this observational study was to evaluate screening and progression of diabetic retinopathy during pregnancy in women with pregestational diabetes attending five antenatal centres along the Irish Atlantic seaboard. An adequate frequency of screening was defined as at least two retinal evaluations in separate trimesters. Progression was defined as at least one stage of deterioration of diabetic retinopathy and/or development of diabetic macular edema on at least one eye. Women with pregestational diabetes who delivered after 22 gestational weeks (n = 307) were included. In total, 185 (60.3%) had an adequate number of retinal examinations. Attendance at prepregnancy care was associated with receiving adequate screening (odds ratio 6.23; CI 3.39-11.46 (P < 0.001)). Among those who received adequate evaluations (n = 185), 48 (25.9%) had retinopathy progression. Increasing booking systolic blood pressure (OR 1.03, CI 1.01-1.06, P = 0.02) and greater drop in HbA1c between first and third trimesters of pregnancy (OR 2.05, CI 1.09-3.87, P = 0.03) significantly increased the odds of progression. A significant proportion of women continue to demonstrate retinopathy progression during pregnancy. This study highlights the role of prepregnancy care and the importance of close monitoring during pregnancy and identifies those patients at the highest risk for retinopathy progression.en
dc.language.isoenen
dc.publisherJournal of diabetes researchen
dc.rightsArchived with thanks to Journal of diabetes researchen
dc.subjectDIABETES MELLITUSen
dc.subjectPREGNANCYen
dc.subjectEYE DISORDERSen
dc.titleDiabetic retinopathy in pregnancy: a population-based study of women with pregestational diabetes.en
dc.typeArticleen
dc.identifier.journalJournal of diabetes researchen
dc.description.fundingHRB Health Research Boarden
dc.description.provinceConnachten
dc.description.peer-reviewpeer-reviewen

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