National Hepatitis C Database for infection acquired through blood and blood products

Hdl Handle:
http://hdl.handle.net/10147/575439
Title:
National Hepatitis C Database for infection acquired through blood and blood products
Authors:
Health Protection Surveillance Centre
Affiliation:
Health Service Executive (HSE)
Publisher:
Health Protection Surveillance Centre (HPSC)
Issue Date:
2012
URI:
http://hdl.handle.net/10147/575439
Item Type:
Report
Language:
en
Description:
Main findings Profile of participants • There are 1316 database participants, a participation rate of 77%. • The source of infection was anti-D immunoglobulin in 61%, blood transfusion or treatment for renal disease in 26% and blood clotting factors in 13%. • The average age at last follow-up was 57 years. • The average time interval from infection to last follow-up was 30 years. Hepatitis C status • 48% of participants were still chronically infected at the time of last testing. • The spontaneous viral clearance rate in this population is between 19% and 36% (having taken account of those who died before RNA testing, and allowing for the possibility that some participants may have had false positive screening test results). • Females were more likely to have cleared the virus spontaneously. • The most common genotype is genotype 1 (76%), followed by genotype 3 (18%). Alcohol consumption • Alcohol consumption in excess of recommended levels was recorded for 15% of those chronically infected. This was higher in males and in younger people. Outcomes Cirrhosis • Cirrhosis had developed in 137 participants (17%) who ever had chronic infection, at an average duration of infection of 24 years and an average age of 53 years. This was an increase of 26 cases since the last round of data collection.
Keywords:
INFECTION CONTROL; BLOOD; HEPATITIS C
ISSN:
978-0-9551236-2-7

Full metadata record

DC FieldValue Language
dc.contributor.authorHealth Protection Surveillance Centreen
dc.date.accessioned2015-08-21T10:40:02Zen
dc.date.available2015-08-21T10:40:02Zen
dc.date.issued2012en
dc.identifier.issn978-0-9551236-2-7en
dc.identifier.urihttp://hdl.handle.net/10147/575439en
dc.descriptionMain findings Profile of participants • There are 1316 database participants, a participation rate of 77%. • The source of infection was anti-D immunoglobulin in 61%, blood transfusion or treatment for renal disease in 26% and blood clotting factors in 13%. • The average age at last follow-up was 57 years. • The average time interval from infection to last follow-up was 30 years. Hepatitis C status • 48% of participants were still chronically infected at the time of last testing. • The spontaneous viral clearance rate in this population is between 19% and 36% (having taken account of those who died before RNA testing, and allowing for the possibility that some participants may have had false positive screening test results). • Females were more likely to have cleared the virus spontaneously. • The most common genotype is genotype 1 (76%), followed by genotype 3 (18%). Alcohol consumption • Alcohol consumption in excess of recommended levels was recorded for 15% of those chronically infected. This was higher in males and in younger people. Outcomes Cirrhosis • Cirrhosis had developed in 137 participants (17%) who ever had chronic infection, at an average duration of infection of 24 years and an average age of 53 years. This was an increase of 26 cases since the last round of data collection.en
dc.language.isoenen
dc.publisherHealth Protection Surveillance Centre (HPSC)en
dc.subjectINFECTION CONTROLen
dc.subjectBLOODen
dc.subjectHEPATITIS Cen
dc.titleNational Hepatitis C Database for infection acquired through blood and blood productsen
dc.typeReporten
dc.contributor.departmentHealth Service Executive (HSE)en
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