Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA).

Hdl Handle:
http://hdl.handle.net/10147/575051
Title:
Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA).
Authors:
Murphy, Catriona; Bennett, Kathleen; Fahey, Tom; Shelley, Emer; Graham, Ian; Kenny, Rose Anne
Citation:
Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA). 2015, 5 (7):e008017 BMJ Open
Publisher:
BMJ Open
Journal:
BMJ open
Issue Date:
Jul-2015
URI:
http://hdl.handle.net/10147/575051
DOI:
10.1136/bmjopen-2015-008017
PubMed ID:
26169806
Abstract:
This study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE).; This study is cross-sectional in design using data from the first wave (2009-2011) of The Irish Longitudinal Study on Ageing (TILDA).; The sample (n=3372) is representative of community living adults aged 50-64 years in Ireland.; Statins were used by 68.6% (95% CI 61.5% to 75.8%) of those with known CVD, 57.4% (95% CI 49.1% to 65.7%) of those with known diabetes and by 19.7% (95% CI 13.0% to 26.3%) of adults with a SCORE risk ≥5%. Over a third (38.5%, 95% CI 31.0% to 46.0%) of those with known CVD, 46.8% (95% CI 38.4% to 55.1%) of those with known diabetes and 85.2% (95% CI 79.3% to 91.1%) of those with a SCORE risk ≥5% were at or above the low-density lipoprotein cholesterol (LDL-C) target of 2.5 mmol/L specified in the 2007 European guidelines.; Despite strong evidence and clinical guidelines recommending the use of statins for secondary prevention, a gap exists between guidelines and practice in this cohort. It is also of concern that a low proportion of adults with a SCORE risk ≥5% were taking statins. A policy response that strengthens secondary prevention, and improves risk assessment and shared decision-making in the primary prevention of CVD is required.
Item Type:
Article
Language:
en
Description:
Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA)
Keywords:
CARDIOVASCULAR DISEASE; OLDER PEOPLE
ISSN:
2044-6055

Full metadata record

DC FieldValue Language
dc.contributor.authorMurphy, Catrionaen
dc.contributor.authorBennett, Kathleenen
dc.contributor.authorFahey, Tomen
dc.contributor.authorShelley, Emeren
dc.contributor.authorGraham, Ianen
dc.contributor.authorKenny, Rose Anneen
dc.date.accessioned2015-08-18T12:08:40Zen
dc.date.available2015-08-18T12:08:40Zen
dc.date.issued2015-07en
dc.identifier.citationStatin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA). 2015, 5 (7):e008017 BMJ Openen
dc.identifier.issn2044-6055en
dc.identifier.pmid26169806en
dc.identifier.doi10.1136/bmjopen-2015-008017en
dc.identifier.urihttp://hdl.handle.net/10147/575051en
dc.descriptionStatin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA)en
dc.description.abstractThis study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE).en
dc.description.abstractThis study is cross-sectional in design using data from the first wave (2009-2011) of The Irish Longitudinal Study on Ageing (TILDA).en
dc.description.abstractThe sample (n=3372) is representative of community living adults aged 50-64 years in Ireland.en
dc.description.abstractStatins were used by 68.6% (95% CI 61.5% to 75.8%) of those with known CVD, 57.4% (95% CI 49.1% to 65.7%) of those with known diabetes and by 19.7% (95% CI 13.0% to 26.3%) of adults with a SCORE risk ≥5%. Over a third (38.5%, 95% CI 31.0% to 46.0%) of those with known CVD, 46.8% (95% CI 38.4% to 55.1%) of those with known diabetes and 85.2% (95% CI 79.3% to 91.1%) of those with a SCORE risk ≥5% were at or above the low-density lipoprotein cholesterol (LDL-C) target of 2.5 mmol/L specified in the 2007 European guidelines.en
dc.description.abstractDespite strong evidence and clinical guidelines recommending the use of statins for secondary prevention, a gap exists between guidelines and practice in this cohort. It is also of concern that a low proportion of adults with a SCORE risk ≥5% were taking statins. A policy response that strengthens secondary prevention, and improves risk assessment and shared decision-making in the primary prevention of CVD is required.en
dc.language.isoenen
dc.publisherBMJ Openen
dc.rightsArchived with thanks to BMJ openen
dc.subjectCARDIOVASCULAR DISEASEen
dc.subjectOLDER PEOPLEen
dc.titleStatin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA).en
dc.typeArticleen
dc.identifier.journalBMJ openen

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