Left atrial appendage thrombus with resulting stroke post-RF ablation for atrial fibrillation in a patient on dabigatran.

Hdl Handle:
http://hdl.handle.net/10147/559259
Title:
Left atrial appendage thrombus with resulting stroke post-RF ablation for atrial fibrillation in a patient on dabigatran.
Authors:
Lobo, R; McCann, C; Hussaini, A; Meany, T B; Kiernan, T J
Citation:
Left atrial appendage thrombus with resulting stroke post-RF ablation for atrial fibrillation in a patient on dabigatran., 107 (10):329-30 Ir Med J
Publisher:
Irish Medical Journal
Journal:
Irish medical journal
Issue Date:
Nov-2015
URI:
http://hdl.handle.net/10147/559259
PubMed ID:
25551903
Abstract:
Dabigatran etexilate is licensed for use in prevention of deep venous thromboembolism and in prevention of stroke and systemic embolism in nonvalvular atrial fibrillation (AF). It has also been used in patients for other indications as a substitute for warfarin therapy because it requires no monitoring; one group being patients undergoing radiofrequency (RF), ablation for AF, although there have been no consensus guidelines with regards to dosage and timing of dose. We report the case of a patient with documentary evidence of left atrial appendage (LAA) thrombus formation and neurological sequelae post-RF ablation despite being on dabigatran. This case highlights the concern that periprocedural dabigatran may not provide adequate protection from development of LAA thrombus and that a standardised protocol will need to be developed and undergo large multicentre trials before dabigatran can be safely used for patients undergoing RF-ablation.
Item Type:
Article
Language:
en
Keywords:
HEART DISEASE; STROKE PREVENTION
MeSH:
Antithrombins; Atrial Appendage; Atrial Fibrillation; Benzimidazoles; Catheter Ablation; Coronary Thrombosis; Drug Interactions; Female; Humans; Middle Aged; Stroke; beta-Alanine
ISSN:
0332-3102

Full metadata record

DC FieldValue Language
dc.contributor.authorLobo, Ren
dc.contributor.authorMcCann, Cen
dc.contributor.authorHussaini, Aen
dc.contributor.authorMeany, T Ben
dc.contributor.authorKiernan, T Jen
dc.date.accessioned2015-07-08T13:51:40Zen
dc.date.available2015-07-08T13:51:40Zen
dc.date.issued2015-11en
dc.identifier.citationLeft atrial appendage thrombus with resulting stroke post-RF ablation for atrial fibrillation in a patient on dabigatran., 107 (10):329-30 Ir Med Jen
dc.identifier.issn0332-3102en
dc.identifier.pmid25551903en
dc.identifier.urihttp://hdl.handle.net/10147/559259en
dc.description.abstractDabigatran etexilate is licensed for use in prevention of deep venous thromboembolism and in prevention of stroke and systemic embolism in nonvalvular atrial fibrillation (AF). It has also been used in patients for other indications as a substitute for warfarin therapy because it requires no monitoring; one group being patients undergoing radiofrequency (RF), ablation for AF, although there have been no consensus guidelines with regards to dosage and timing of dose. We report the case of a patient with documentary evidence of left atrial appendage (LAA) thrombus formation and neurological sequelae post-RF ablation despite being on dabigatran. This case highlights the concern that periprocedural dabigatran may not provide adequate protection from development of LAA thrombus and that a standardised protocol will need to be developed and undergo large multicentre trials before dabigatran can be safely used for patients undergoing RF-ablation.en
dc.language.isoenen
dc.publisherIrish Medical Journalen
dc.rightsArchived with thanks to Irish medical journalen
dc.subjectHEART DISEASEen
dc.subjectSTROKE PREVENTIONen
dc.subject.meshAntithrombinsen
dc.subject.meshAtrial Appendageen
dc.subject.meshAtrial Fibrillationen
dc.subject.meshBenzimidazolesen
dc.subject.meshCatheter Ablationen
dc.subject.meshCoronary Thrombosisen
dc.subject.meshDrug Interactionsen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMiddle Ageden
dc.subject.meshStrokeen
dc.subject.meshbeta-Alanineen
dc.titleLeft atrial appendage thrombus with resulting stroke post-RF ablation for atrial fibrillation in a patient on dabigatran.en
dc.typeArticleen
dc.identifier.journalIrish medical journalen
dc.description.fundingNo fundingen
dc.description.provinceMunsteren
dc.description.peer-reviewpeer-reviewen

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